TOX4 and EXOSC10

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOX4	EXOSC10
Gene Name		TOX high mobility group box family member 4	exosome component 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleoplasm PTW/PP1 Phosphatase Complex	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Transcriptionally Active Chromatin
	Molecular Function	DNA Binding Chromatin Binding Protein Binding	Nucleotide Binding Exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity Poly(A) RNA Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription, DNA-templated	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Nuclear MRNA Surveillance CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Histone MRNA Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ATXN1 BANP CCBE1 CREB1 EXOSC10 FNDC3B GEMIN6 HIPK3 MYL7 PPP1CA TBX6 WDR82 ZMYND19 ZNF512B	35 interactors: ALDH1B1 B9D1 CHPF CIB1 DIS3 DXO EIF3M EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 FERMT3 FOXRED1 IMMT LCAT LSM2 LSM8 MPHOSPH6 MPP6 NOMO1 NOMO2 PTGES2 RPE RUVBL2 SCRIB SKIV2L SSRP1 TARDBP TOX4 UPF2 USP16 USP21 XRN1 XRN2
Entrez ID		9878	5394
HPRD ID		12661	16180
Ensembl ID		ENSG00000092203	ENSG00000171824
Uniprot IDs		O94842	Q01780 Q96G78
PDB IDs			2CPR 3SAF 3SAG 3SAH
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Lung Development Nucleobase-containing Compound Metabolic Process Respiratory Tube Development Transcription, DNA-templated Lung Alveolus Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Respiratory System Development Regulation Of Gene Expression RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Lymphangiogenesis Negative Regulation Of Neuron Maturation Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process RNA Processing Circadian Rhythm Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Neuron Maturation Nuclear MRNA Surveillance Regulation Of Cellular Response To Growth Factor Stimulus Tube Development Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway RNA Surveillance Negative Regulation Of Transcription By Competitive Promoter Binding Regulation Of Glycogen Catabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Intracellular MRNA Localization Venous Blood Vessel Morphogenesis Dosage Compensation RRNA Catabolic Process Negative Regulation Of JUN Kinase Activity Lymphangiogenesis Lung Saccule Development Learning Or Memory Lymph Vessel Morphogenesis Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription MRNA Transcription Regulation Of RNA Biosynthetic Process	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Metabolic Process RRNA Metabolic Process RRNA Processing Aromatic Compound Catabolic Process Cellular Macromolecule Catabolic Process Ribosome Biogenesis Ribonucleoprotein Complex Biogenesis RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Catabolic Process RNA Metabolic Process NcRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear MRNA Surveillance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Deamination RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Gene Expression Maturation Of 5.8S RRNA Histone MRNA Catabolic Process RRNA Catabolic Process Cellular Metabolic Process DNA Modification Protein K63-linked Deubiquitination Histone Deubiquitination Histone MRNA Metabolic Process DNA Metabolic Process Chromatin Modification Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Male Germ Cell Proliferation Metabolic Process Chromatin Remodeling MRNA Processing Regulation Of RNA Stability Chromatin Organization Thrombopoietin-mediated Signaling Pathway Posttranscriptional Regulation Of Gene Expression Histone H2A K63-linked Deubiquitination Regulation Of Male Germ Cell Proliferation Endomitotic Cell Cycle
Tagcloud ?		actors adducts attached beads damaged damaging expand fishing hmg hmgb1 hubf interactome mediation nanohplc oxaliplatin pharmacology plasmids plasmon platinated platinating pnuts satraplatin spri subproteome succeeded unexpected wd wdr82	18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Difference) ?		actors adducts attached beads damaged damaging expand fishing hmg hmgb1 hubf interactome mediation nanohplc oxaliplatin pharmacology plasmids plasmon platinated platinating pnuts satraplatin spri subproteome succeeded unexpected wd wdr82	18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Intersection) ?