TOX4 and GEMIN6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TOX4	GEMIN6
Description		TOX high mobility group box family member 4	gem nuclear organelle associated protein 6
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Chromosome PTW/PP1 Phosphatase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies
	Molecular Function	DNA Binding Protein Binding Chromatin DNA Binding	RNA Binding Protein Binding
	Biological Process	RNA Polymerase II Promoter Clearance Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Transcription Elongation By RNA Polymerase II	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: ATXN1 BANP CCBE1 CREB1 EXOSC10 FNDC3B GEMIN6 HIPK3 HSPB1 MYL7 PPP1CA QRICH1 TBX6 WDR82 ZMYND19 ZNF512B	16 interacting genes: ACOT11 DDIT4L GEMIN7 NUFIP1 RASL11B RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STRAP TOX4
Entrez ID		9878	79833
HPRD ID		12661	06110
Ensembl ID		ENSG00000092203	ENSG00000152147
Uniprot IDs		O94842	Q8WXD5
PDB IDs			1Y96 7BBL
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Promoter Clearance PTW/PP1 Phosphatase Complex RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription, Elongation DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Glial Cell Proliferation Chemotaxis To Arachidonate RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Protein Kinase C Signaling RNA Surveillance Nuclear RNA Surveillance Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Metabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Transforming Growth Factor Beta3 Production Visual Behavior Nucleic Acid Metabolic Process Visual Learning Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Transcription Euchromatin RNA Binding Nuclear Polyadenylation-dependent SnoRNA Catabolic Process Nuclear Polyadenylation-dependent SnRNA Catabolic Process Nuclear Polyadenylation-dependent CUT Catabolic Process Positive Regulation Of DNA-templated Transcription, Elongation RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Transcription Elongation By RNA Polymerase II LncRNA Catabolic Process Negative Regulation Of LncRNA Transcription MRNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleus Transcription By RNA Polymerase II Response To Dehydroepiandrosterone Positive Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process	SMN-Sm Protein Complex 7-methylguanosine Cap Hypermethylation Spliceosomal SnRNP Assembly U2 SnRNP U4 SnRNP Methylosome Protein-RNA Complex Assembly Small Nuclear Ribonucleoprotein Complex U1 SnRNP U7 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions PICln-Sm Protein Complex RNA Methylation Catalytic Step 2 Spliceosome RNA Splicing Macromolecule Methylation Protein-containing Complex Assembly MRNA Processing Precatalytic Spliceosome Protein-containing Complex Organization RNA Modification Spliceosomal Complex RNA Processing Methylation MRNA Metabolic Process Ribonucleoprotein Complex U2 SnRNP Binding Cellular Component Assembly Telomerase Holoenzyme Complex RNA Metabolic Process RNA Binding Histone Pre-mRNA DCP Binding Spliceosomal Tri-snRNP Complex Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process SMN Complex U2-type Prespliceosome Telomerase RNA Binding Protein Methylation Pre-mRNA Branch Point Binding MRNA Branch Site Recognition
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