PLEKHM1 and MOB4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLEKHM1	MOB4
Gene Name		pleckstrin homology domain containing, family M (with RUN domain) member 1	MOB family member 4, phocein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytoplasm Golgi Apparatus Cytosol Golgi Cisterna Membrane Neuronal Cell Body Dendritic Spine Perinuclear Region Of Cytoplasm
	Molecular Function	Metal Ion Binding	Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Intracellular Signal Transduction	Transport
Pathways
Drugs
Diseases
GWAS		Parkinson's disease ( 20070850)
Protein-Protein Interactions		8 interactors: BID EIF2S2 GADD45G MAPK6 MOB4 MUC2 PAFAH1B3 SERPINB9	31 interactors: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2
Entrez ID		9842	25843
HPRD ID		11439	10165
Ensembl ID		ENSG00000225190	ENSG00000115540
Uniprot IDs		Q9Y4G2	B4DM50 Q9Y3A3
PDB IDs
Enriched GO Terms of Interacting Partners?			Developmental Process Anatomical Structure Development Cell Differentiation Positive Regulation Of Protein Metabolic Process Multicellular Organismal Development Regulation Of Metabolic Process Regulation Of Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cellular Metabolic Process Hippo Signaling Regulation Of Protein Metabolic Process Regulation Of Neuron Projection Development Signal Transduction Positive Regulation Of Neuron Projection Development System Development Cellular Response To Stimulus Regulation Of Cellular Component Organization Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Signaling Neurogenesis Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cell Projection Organization Regulation Of Cell Projection Organization Cell Communication Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Neuron Projection Development Regulation Of Phosphorus Metabolic Process Cellular Response To Organic Substance Nervous System Development Cell Projection Organization Regulation Of Signal Transduction Cell Projection Morphogenesis Response To Stimulus Positive Regulation Of Catalytic Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Cell Part Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cell Death
Tagcloud ?		ablated c1 cathepsin colocalizes ctx declined depleted disorganized dynein hydrolase lis1 lysosomal lysosome master microtubule microtubules nfat organization osteoclast osteoclasts pits polykaryons rankl resorption secretion shrna specialized unrecognized virtue
Tagcloud (Difference) ?		ablated c1 cathepsin colocalizes ctx declined depleted disorganized dynein hydrolase lis1 lysosomal lysosome master microtubule microtubules nfat organization osteoclast osteoclasts pits polykaryons rankl resorption secretion shrna specialized unrecognized virtue
Tagcloud (Intersection) ?