MOB4 and DNM1

Number of citations of the paper that reports this interaction (PMID 11872741)
14

Data Source:
HPRD (in vitro)

		MOB4	DNM1
Gene Name		MOB family member 4, phocein	dynamin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Golgi Cisterna Membrane Neuronal Cell Body Dendritic Spine Perinuclear Region Of Cytoplasm	Microtubule Plasma Membrane Membrane Coat Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding Protein Kinase Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding Nitric-oxide Synthase Binding
	Biological Process	Transport	Endocytosis Receptor-mediated Endocytosis Endosome Organization Axon Guidance Receptor Internalization Ephrin Receptor Signaling Pathway Clathrin-mediated Endocytosis
Pathways			Retrograde neurotrophin signalling Signalling by NGF Formation of annular gap junctions Axon guidance Gap junction degradation Gap junction trafficking L1CAM interactions NGF signalling via TRKA from the plasma membrane Recycling pathway of L1 Toll-Like Receptors Cascades EPH-ephrin mediated repulsion of cells Toll Like Receptor 4 (TLR4) Cascade Gap junction trafficking and regulation MHC class II antigen presentation EPH-Ephrin signaling Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		31 interactors: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2	47 interactors: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GNB2L1 GRB2 GRIN1 GRIN2D ITSN1 KIAA1377 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP SH3GL1 SH3GL2 SH3GL3 SH3GLB1 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I
Entrez ID		25843	1759
HPRD ID		10165	03851
Ensembl ID		ENSG00000115540	ENSG00000106976
Uniprot IDs		B4DM50 Q9Y3A3	Q05193
PDB IDs			1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS
Enriched GO Terms of Interacting Partners?		Developmental Process Anatomical Structure Development Cell Differentiation Positive Regulation Of Protein Metabolic Process Multicellular Organismal Development Regulation Of Metabolic Process Regulation Of Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cellular Metabolic Process Hippo Signaling Regulation Of Protein Metabolic Process Regulation Of Neuron Projection Development Signal Transduction Positive Regulation Of Neuron Projection Development System Development Cellular Response To Stimulus Regulation Of Cellular Component Organization Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Signaling Neurogenesis Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cell Projection Organization Regulation Of Cell Projection Organization Cell Communication Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Neuron Projection Development Regulation Of Phosphorus Metabolic Process Cellular Response To Organic Substance Nervous System Development Cell Projection Organization Regulation Of Signal Transduction Cell Projection Morphogenesis Response To Stimulus Positive Regulation Of Catalytic Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Cell Part Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cell Death	Endocytosis Vesicle-mediated Transport Regulation Of Cellular Component Organization Positive Regulation Of Protein Complex Assembly Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Cellular Component Assembly Neuron Projection Morphogenesis Positive Regulation Of Cellular Component Biogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Membrane Organization Transport Axon Guidance Cell Projection Organization Regulation Of Signaling Neuron Projection Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Protein Complex Assembly Vascular Endothelial Growth Factor Receptor Signaling Pathway Chemotaxis Synaptic Vesicle Transport Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Neuron Development Generation Of Neurons Membrane Tubulation Signaling Axonogenesis Anatomical Structure Development Protein Complex Assembly Neurogenesis Cell Communication Anatomical Structure Morphogenesis Locomotion Neurotrophin TRK Receptor Signaling Pathway Synaptic Vesicle Endocytosis Cell Morphogenesis Involved In Differentiation Axon Development Enzyme Linked Receptor Protein Signaling Pathway Synaptic Vesicle Recycling Regulation Of Signal Transduction Neurotrophin Signaling Pathway Regulation Of Phosphorylation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Positive Regulation Of Metabolic Process Neuron Differentiation Negative Regulation Of Endocytosis
Tagcloud ?			a432t a452v ankk1 arrb2 cdh13 chrna2 chrna9 dbh drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss
Tagcloud (Difference) ?			a432t a452v ankk1 arrb2 cdh13 chrna2 chrna9 dbh drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss
Tagcloud (Intersection) ?