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MOB4 and ARHGEF15
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
MOB4
ARHGEF15
Gene Name
MOB family member 4, phocein
Rho guanine nucleotide exchange factor (GEF) 15
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Golgi Apparatus
Cytosol
Golgi Cisterna Membrane
Neuronal Cell Body
Dendritic Spine
Perinuclear Region Of Cytoplasm
Cytoplasm
Dendrite
Molecular Function
Protein Binding
Kinase Binding
Metal Ion Binding
Rho Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Biological Process
Transport
Positive Regulation Of Rho GTPase Activity
Regulation Of Catalytic Activity
Positive Regulation Of Stress Fiber Assembly
Retina Vasculature Morphogenesis In Camera-type Eye
Negative Regulation Of Synapse Maturation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
31 interactors:
ARHGEF15
CCDC85B
CRMP1
DNM1
EGFR
EGLN2
ELK1
EPS15
FADD
FBLN1
GDF9
KIDINS220
LATS1
LATS2
LRIF1
MCM2
MED10
MED31
MYL6
MYO9B
NME2
PAICS
PLEKHM1
PTPRS
RAPGEF2
SCMH1
SETDB1
STK11
STK3
THAP4
UBE2V2
8 interactors:
C11orf49
CEP55
EPHA4
ESR1
ESRRG
LASP1
MOB4
PIN1
Entrez ID
25843
22899
HPRD ID
10165
10535
Ensembl ID
ENSG00000115540
ENSG00000198844
Uniprot IDs
B4DM50
Q9Y3A3
O94989
PDB IDs
Enriched GO Terms of Interacting Partners
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Developmental Process
Anatomical Structure Development
Cell Differentiation
Positive Regulation Of Protein Metabolic Process
Multicellular Organismal Development
Regulation Of Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Hippo Signaling
Regulation Of Protein Metabolic Process
Regulation Of Neuron Projection Development
Signal Transduction
Positive Regulation Of Neuron Projection Development
System Development
Cellular Response To Stimulus
Regulation Of Cellular Component Organization
Generation Of Neurons
Regulation Of Cellular Protein Metabolic Process
Signaling
Neurogenesis
Regulation Of Phosphorylation
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cell Projection Organization
Regulation Of Cell Projection Organization
Cell Communication
Regulation Of Protein Kinase Activity
Regulation Of Protein Phosphorylation
Regulation Of Kinase Activity
Regulation Of Neuron Differentiation
Positive Regulation Of Neuron Differentiation
Neuron Projection Development
Regulation Of Phosphorus Metabolic Process
Cellular Response To Organic Substance
Nervous System Development
Cell Projection Organization
Regulation Of Signal Transduction
Cell Projection Morphogenesis
Response To Stimulus
Positive Regulation Of Catalytic Activity
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Cell Differentiation
Positive Regulation Of Phosphorylation
Cell Part Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Cell Death
Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Steroid Hormone Mediated Signaling Pathway
Fasciculation Of Motor Neuron Axon
Hormone-mediated Signaling Pathway
Fasciculation Of Sensory Neuron Axon
Prostate Epithelial Cord Elongation
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Negative Regulation Of Axon Regeneration
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Intracellular Receptor Signaling Pathway
Branch Elongation Involved In Mammary Gland Duct Branching
Antral Ovarian Follicle Growth
DNA-templated Transcription, Initiation
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Mammary Gland Branching Involved In Pregnancy
Regulation Of Rho GTPase Activity
Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis
Positive Regulation Of Cellular Metabolic Process
Regulation Of Rho Protein Signal Transduction
Corticospinal Tract Morphogenesis
Vagina Development
Positive Regulation Of Signal Transduction
Regulation Of Axon Regeneration
Uterus Development
Regulation Of Signal Transduction
Cellular Response To Organic Cyclic Compound
Intracellular Estrogen Receptor Signaling Pathway
Positive Regulation Of Nitric-oxide Synthase Activity
Cell Separation After Cytokinesis
Regulation Of Rap GTPase Activity
Cellular Response To Estradiol Stimulus
Prostate Gland Growth
Regulation Of Rac GTPase Activity
Branching Involved In Prostate Gland Morphogenesis
Negative Regulation Of Intracellular Signal Transduction
Cellular Response To Lipid
Mammary Gland Epithelial Cell Proliferation
Female Genitalia Development
Axonal Fasciculation
Regulation Of Rap Protein Signal Transduction
Regulation Of Signaling
Positive Regulation Of Monooxygenase Activity
Branch Elongation Of An Epithelium
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Tagcloud (Intersection)
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