MOB4 and KIDINS220

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MOB4	KIDINS220
Gene Name		MOB family member 4, phocein	kinase D-interacting substrate, 220kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Golgi Cisterna Membrane Neuronal Cell Body Dendritic Spine Perinuclear Region Of Cytoplasm	Nucleoplasm Late Endosome Cytosol Membrane Integral Component Of Membrane Protein Complex
	Molecular Function	Protein Binding Kinase Binding Metal Ion Binding	PDZ Domain Binding
	Biological Process	Transport	Activation Of MAPKK Activity In Utero Embryonic Development Positive Regulation Of Neuron Projection Development Cytoplasmic Transport Nerve Growth Factor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Dendrite Morphogenesis Cellular Response To Nerve Growth Factor Stimulus
Pathways			ARMS-mediated activation Signalling to ERKs Signalling by NGF Prolonged ERK activation events NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS			Neutrophil count ( 21507922)
Protein-Protein Interactions		31 interactors: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2	9 interactors: CDC73 CRKL MOB4 MYC NGFR NTRK1 NTRK2 NTRK3 PRKD1
Entrez ID		25843	57498
HPRD ID		10165	17235
Ensembl ID		ENSG00000115540	ENSG00000134313
Uniprot IDs		B4DM50 Q9Y3A3	Q7Z322 Q9ULH0
PDB IDs
Enriched GO Terms of Interacting Partners?		Developmental Process Anatomical Structure Development Cell Differentiation Positive Regulation Of Protein Metabolic Process Multicellular Organismal Development Regulation Of Metabolic Process Regulation Of Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cellular Metabolic Process Hippo Signaling Regulation Of Protein Metabolic Process Regulation Of Neuron Projection Development Signal Transduction Positive Regulation Of Neuron Projection Development System Development Cellular Response To Stimulus Regulation Of Cellular Component Organization Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Signaling Neurogenesis Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cell Projection Organization Regulation Of Cell Projection Organization Cell Communication Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Neuron Projection Development Regulation Of Phosphorus Metabolic Process Cellular Response To Organic Substance Nervous System Development Cell Projection Organization Regulation Of Signal Transduction Cell Projection Morphogenesis Response To Stimulus Positive Regulation Of Catalytic Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Cell Part Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cell Death	Cellular Response To Growth Factor Stimulus Response To Growth Factor Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Neuron Projection Development Cellular Response To Organic Substance Positive Regulation Of Cell Projection Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Neuron Differentiation Regulation Of Cell Proliferation Regulation Of Neuron Projection Development Response To Organic Substance Positive Regulation Of Neurogenesis Regulation Of Cell Differentiation Regulation Of Signal Transduction Circadian Rhythm Negative Regulation Of Cell Death Regulation Of Cell Projection Organization Positive Regulation Of Cell Development Regulation Of Signaling Regulation Of Neuron Differentiation Protein Autophosphorylation Neurotrophin TRK Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Positive Regulation Of Protein Metabolic Process Mechanoreceptor Differentiation Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Axonogenesis Regulation Of Neurogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Phosphorylation Rhythmic Process Regulation Of Catalytic Activity Anatomical Structure Morphogenesis Regulation Of Phosphorus Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Positive Regulation Of Cell Proliferation Regulation Of Fibroblast Proliferation Regulation Of Cell Development Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Modification Process
Tagcloud ?			acts ankyrin arms cdk cdk4 cdks cyclins ephrin g1 hyperphosphorylation interacting nervous neuroblastoma neurotrophin never organizing platform prb primarily prominent regulate repeat rich scaffold slowdown spanning tightly upregulation
Tagcloud (Difference) ?			acts ankyrin arms cdk cdk4 cdks cyclins ephrin g1 hyperphosphorylation interacting nervous neuroblastoma neurotrophin never organizing platform prb primarily prominent regulate repeat rich scaffold slowdown spanning tightly upregulation
Tagcloud (Intersection) ?