PLEKHM1 and MUC2

Number of citations of the paper that reports this interaction (PMID 12820725)
1

Data Source:
HPRD (in vitro)

		PLEKHM1	MUC2
Gene Name		pleckstrin homology domain containing, family M (with RUN domain) member 1	mucin 2, oligomeric mucus/gel-forming
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Golgi Lumen Inner Mucus Layer Outer Mucus Layer
	Molecular Function	Metal Ion Binding	Protein Binding
	Biological Process	Intracellular Signal Transduction	Protein O-linked Glycosylation O-glycan Processing Maintenance Of Gastrointestinal Epithelium Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Post-translational protein modification Termination of O-glycan biosynthesis O-linked glycosylation of mucins O-linked glycosylation
Drugs			Pranlukast
Diseases
GWAS		Parkinson's disease ( 20070850)	Interstitial lung disease ( 23583980)
Protein-Protein Interactions		8 interactors: BID EIF2S2 GADD45G MAPK6 MOB4 MUC2 PAFAH1B3 SERPINB9	4 interactors: GALNT12 GALNT14 MLH1 PLEKHM1
Entrez ID		9842	4583
HPRD ID		11439	11828
Ensembl ID		ENSG00000225190	ENSG00000198788
Uniprot IDs		Q9Y4G2	Q02817
PDB IDs
Enriched GO Terms of Interacting Partners?			O-glycan Processing Protein O-linked Glycosylation Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Negative Regulation Of Mitotic Recombination Post-translational Protein Modification Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Macromolecule Glycosylation Protein Glycosylation Glycosylation Spindle Midzone Assembly Glycoprotein Biosynthetic Process Resolution Of Meiotic Recombination Intermediates Glycoprotein Metabolic Process Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Nuclear-transcribed MRNA Poly(A) Tail Shortening Isotype Switching Metaphase Plate Congression Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Establishment Of Chromosome Localization Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Reciprocal Meiotic Recombination B Cell Activation Involved In Immune Response Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Synapsis Mismatch Repair Homologous Chromosome Segregation Male Meiosis Immunoglobulin Production Carbohydrate Metabolic Process Regulation Of DNA Recombination Oogenesis MRNA 3'-end Processing Meiotic Chromosome Segregation Spindle Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of DNA Metabolic Process See more
Tagcloud ?		ablated c1 cathepsin colocalizes ctx declined depleted disorganized dynein hydrolase lis1 lysosomal lysosome master microtubule microtubules nfat organization osteoclast osteoclasts pits polykaryons rankl resorption secretion shrna specialized unrecognized virtue	barrett cdx1 columnar dnmaml esophagus formerly goblet hes1 jag1 k13 k14 k18 k19 k20 k5 k8 keratins klf4 mastermind metaplasia muc17 muc3b muc5b mucins notch notch2 notch3 organotypic transdifferentiation
Tagcloud (Difference) ?		ablated c1 cathepsin colocalizes ctx declined depleted disorganized dynein hydrolase lis1 lysosomal lysosome master microtubule microtubules nfat organization osteoclast osteoclasts pits polykaryons rankl resorption secretion shrna specialized unrecognized virtue	barrett cdx1 columnar dnmaml esophagus formerly goblet hes1 jag1 k13 k14 k18 k19 k20 k5 k8 keratins klf4 mastermind metaplasia muc17 muc3b muc5b mucins notch notch2 notch3 organotypic transdifferentiation
Tagcloud (Intersection) ?