MOB4 and SCMH1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MOB4	SCMH1
Description		MOB family member 4, phocein	Scm polycomb group protein homolog 1
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Membrane Golgi Cisterna Membrane Perinuclear Region Of Cytoplasm FAR/SIN/STRIPAK Complex Postsynapse Glutamatergic Synapse	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Metal Ion Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Negative Regulation Of Hippo Signaling	Regulation Of DNA-templated Transcription Heterochromatin Formation Negative Regulation Of DNA-templated Transcription
Pathways
Drugs			Mercaptoethanol
Diseases
GWAS		Allergic rhinitis ( 31361310) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Schizophrenia ( 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015 30061737) General risk tolerance (MTAG) ( 30643258) Height ( 18391952 20881960 23563607 25282103) Hip circumference adjusted for BMI ( 34021172) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928)
Interacting Genes		32 interacting genes: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 KIDINS220 LATS1 LATS2 LRIF1 MAP4K4 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2	23 interacting genes: EWSR1 FXR1 FXR2 GMNN HK1 HPCAL4 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M RNF2 SFMBT1 SFMBT2 TMEM11 TOB1 TSC1 UBQLN1 UBQLN4
Entrez ID		25843	22955
HPRD ID		10165	11540
Ensembl ID		ENSG00000115540	ENSG00000010803
Uniprot IDs		Q9Y3A3	A0A8Q3SHN2 A0A8Q3SHR9 B3KMZ7 B4DWE6 Q96GD3
PDB IDs		5YF4 7K36	2P0K
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Hippo Signaling Hippo Signaling Regulation Of Growth Regulation Of Hippo Signaling Regulation Of Cell Junction Assembly Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis ATP Binding Nucleotide Binding Negative Regulation Of Growth Regulation Of Macromolecule Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Regulation Of Cell Growth Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Postsynapse Organization Kinase Activity Regulation Of Phosphorylation Negative Regulation Of Canonical Wnt Signaling Pathway Transcription Regulator Activator Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Regulation Of Protein Modification Process Cell Surface Receptor Signaling Pathway Regulation Of Synapse Assembly Developmental Process Endocytic Vesicle Clathrin-coated Pit Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Wnt Signaling Pathway Protein Kinase Activity Regulation Of Intracellular Signal Transduction Regulation Of Metabolic Process Negative Regulation Of Cell Growth Positive Regulation Of DNA-templated Transcription Initiation Establishment Of Endothelial Intestinal Barrier Negative Regulation Of Wnt Signaling Pathway Nerve Growth Factor Signaling Pathway DNA Replication Origin Binding Regulation Of Postsynaptic Density Assembly Positive Regulation Of Cellular Component Biogenesis Protein-containing Complex Assembly Protein Phosphorylation Positive Regulation Of Apoptotic Process Regulation Of DNA-templated Transcription Initiation Protein Serine Kinase Activity Clathrin Coat Assembly Positive Regulation Of Programmed Cell Death Regulation Of Postsynaptic Specialization Assembly	PcG Protein Complex PRC1 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Nucleobase-containing Compound Metabolic Process Sex Chromatin Chromatin Binding Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Metabolic Process Histone Binding Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Transcription Corepressor Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Translation Regulator Activity Negative Regulation Of Biosynthetic Process Nucleus Positive Regulation Of MRNA Catabolic Process Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Gene Expression Positive Regulation Of MRNA Metabolic Process Aggresome Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Glucosamine Kinase Activity Memory T Cell Differentiation Negative Regulation Of Macroautophagy Presynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Store-operated Calcium Channel Activity Polyubiquitin Modification-dependent Protein Binding Maintenance Of ER Location Negative Regulation Of Catabolic Process Nucleoplasm Heterochromatin 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tyrosine Biosynthetic Process Phenylalanine 4-monooxygenase Activity Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Perinuclear Region Of Cytoplasm Regulation Of Macroautophagy Regulation Of MRNA Stability Regulation Of RNA Stability
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