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MOB4 and ELK1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
MOB4
ELK1
Gene Name
MOB family member 4, phocein
ELK1, member of ETS oncogene family
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Golgi Apparatus
Cytosol
Golgi Cisterna Membrane
Neuronal Cell Body
Dendritic Spine
Perinuclear Region Of Cytoplasm
Nucleus
Nucleoplasm
Mitochondrion
Dendrite
Neuronal Cell Body
Axon Terminus
Molecular Function
Protein Binding
Kinase Binding
Metal Ion Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Core Promoter Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Chromatin Binding
Double-stranded DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Biological Process
Transport
Toll-like Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Transcription From RNA Polymerase II Promoter
Response To Light Stimulus
Cell Differentiation
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Neurotrophin TRK Receptor Signaling Pathway
Stress-activated MAPK Cascade
Cellular Response To Testosterone Stimulus
Cellular Response To Gamma Radiation
Positive Regulation Of Neuron Death
Pathways
Toll Like Receptor 7/8 (TLR7/8) Cascade
Toll Like Receptor TLR6:TLR2 Cascade
Toll Like Receptor TLR1:TLR2 Cascade
Activated TLR4 signalling
MyD88 cascade initiated on plasma membrane
Toll Like Receptor 5 (TLR5) Cascade
MyD88 dependent cascade initiated on endosome
MyD88:Mal cascade initiated on plasma membrane
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Toll Like Receptor 9 (TLR9) Cascade
ERK/MAPK targets
Innate Immune System
Signalling by NGF
TRIF-mediated TLR3/TLR4 signaling
MAP kinase activation in TLR cascade
NGF signalling via TRKA from the plasma membrane
MyD88-independent cascade
Toll Like Receptor 2 (TLR2) Cascade
Toll-Like Receptors Cascades
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 3 (TLR3) Cascade
ERK/MAPK targets
Toll Like Receptor 4 (TLR4) Cascade
MAPK targets/ Nuclear events mediated by MAP kinases
Nuclear Events (kinase and transcription factor activation)
Drugs
Diseases
GWAS
Protein-Protein Interactions
31 interactors:
ARHGEF15
CCDC85B
CRMP1
DNM1
EGFR
EGLN2
ELK1
EPS15
FADD
FBLN1
GDF9
KIDINS220
LATS1
LATS2
LRIF1
MCM2
MED10
MED31
MYL6
MYO9B
NME2
PAICS
PLEKHM1
PTPRS
RAPGEF2
SCMH1
SETDB1
STK11
STK3
THAP4
UBE2V2
38 interactors:
APP
BRCA1
CDK6
CEBPB
CREBBP
EMX1
EP300
EWSR1
FBXO25
FLI1
FOS
GRB10
GRB2
HDAC1
HOXB13
ID1
ID2
ID3
KLF4
MAD2L2
MAP2K1
MAP2K3
MAPK1
MAPK10
MAPK11
MAPK14
MAPK3
MAPK8
MAPK9
MOB4
PIAS2
SNCA
SRF
STARD3NL
STK16
TAOK2
UBC
UBE2I
Entrez ID
25843
2002
HPRD ID
10165
02407
Ensembl ID
ENSG00000115540
ENSG00000126767
Uniprot IDs
B4DM50
Q9Y3A3
P19419
Q86SR6
PDB IDs
1DUX
Enriched GO Terms of Interacting Partners
?
Developmental Process
Anatomical Structure Development
Cell Differentiation
Positive Regulation Of Protein Metabolic Process
Multicellular Organismal Development
Regulation Of Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Hippo Signaling
Regulation Of Protein Metabolic Process
Regulation Of Neuron Projection Development
Signal Transduction
Positive Regulation Of Neuron Projection Development
System Development
Cellular Response To Stimulus
Regulation Of Cellular Component Organization
Generation Of Neurons
Regulation Of Cellular Protein Metabolic Process
Signaling
Neurogenesis
Regulation Of Phosphorylation
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cell Projection Organization
Regulation Of Cell Projection Organization
Cell Communication
Regulation Of Protein Kinase Activity
Regulation Of Protein Phosphorylation
Regulation Of Kinase Activity
Regulation Of Neuron Differentiation
Positive Regulation Of Neuron Differentiation
Neuron Projection Development
Regulation Of Phosphorus Metabolic Process
Cellular Response To Organic Substance
Nervous System Development
Cell Projection Organization
Regulation Of Signal Transduction
Cell Projection Morphogenesis
Response To Stimulus
Positive Regulation Of Catalytic Activity
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Cell Differentiation
Positive Regulation Of Phosphorylation
Cell Part Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Cell Death
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Stress-activated MAPK Cascade
Positive Regulation Of Metabolic Process
Stress-activated Protein Kinase Signaling Cascade
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Toll-like Receptor Signaling Pathway
Regulation Of RNA Biosynthetic Process
Cellular Response To Stress
Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Macromolecule Biosynthetic Process
MAPK Cascade
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Regulation Of Signaling
Regulation Of Signal Transduction
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Innate Immune Response
Signal Transduction By Phosphorylation
Response To Growth Factor
Innate Immune Response
Response To Stress
Immune System Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Innate Immune Response
Cellular Response To Organic Substance
Transcription, DNA-templated
Immune Response
Regulation Of Phosphorylation
RNA Biosynthetic Process
Tagcloud
?
activate
activated
atf2
hearts
hypertrophic
ischemia
jnk
jun
kd
mapk
mapkapk2
mapks
mekk1
myocyte
myocytes
perfused
reactivating
reperfusion
rk
sapks
sek1
speculate
stimulates
stresses
subfamily
superfamily
transactivating
transfection
ventricular
Tagcloud (Difference)
?
activate
activated
atf2
hearts
hypertrophic
ischemia
jnk
jun
kd
mapk
mapkapk2
mapks
mekk1
myocyte
myocytes
perfused
reactivating
reperfusion
rk
sapks
sek1
speculate
stimulates
stresses
subfamily
superfamily
transactivating
transfection
ventricular
Tagcloud (Intersection)
?