RADIL and GATA1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RADIL	GATA1
Gene Name		Ras association and DIL domains	GATA binding protein 1 (globin transcription factor 1)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule	Nucleus Nucleoplasm Transcription Factor Complex Transcriptional Repressor Complex
	Molecular Function		Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Transcription Factor Binding Enhancer Sequence-specific DNA Binding P53 Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding DNA Binding, Bending Chromatin DNA Binding Sequence-specific DNA Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Signal Transduction Multicellular Organismal Development Substrate Adhesion-dependent Cell Spreading	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Transcription From RNA Polymerase II Promoter Cell-cell Signaling Blood Coagulation Negative Regulation Of Cell Proliferation Male Gonad Development Regulation Of Glycoprotein Biosynthetic Process Regulation Of Definitive Erythrocyte Differentiation Erythrocyte Differentiation Megakaryocyte Differentiation Platelet Formation Basophil Differentiation Eosinophil Differentiation Negative Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Proliferation Embryonic Hemopoiesis Eosinophil Fate Commitment Negative Regulation Of Apoptotic Process Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Erythrocyte Development Positive Regulation Of Peptidyl-tyrosine Phosphorylation Platelet Aggregation Transcriptional Activation By Promoter-enhancer Looping Dendritic Cell Differentiation Cellular Response To Thyroid Hormone Stimulus Negative Regulation Of Transcription Regulatory Region DNA Binding Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		13 interactors: ASCC2 CEP76 FGFR3 GATA1 KRT31 LITAF MAGEA11 MED19 MRFAP1L1 RHOXF2 SFI1 USP7 YWHAB	51 interactors: AKT1 ARID1A CASP3 CCDC24 CEBPE CREBBP FBF1 FLI1 FRS3 HDAC3 HDAC4 HDAC5 HEXIM2 HEY1 HOXA1 HSPA4 KRTAP10-5 KRTAP9-2 LMO2 MAPK1 MAPK3 MAPK6 MED1 PRKAA1 PRKAB2 RADIL RAI1 SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1 SP1 SPI1 SPIB SRA1 STAT3 SUMO1 TAF7 TAL1 TAX1BP3 TRIM25 TRIM29 ZBTB16 ZBTB22 ZDHHC17 ZFPM1 ZFPM2 ZNF521 ZZZ3
Entrez ID		55698	2623
HPRD ID		07663	02372
Ensembl ID		ENSG00000157927	ENSG00000102145
Uniprot IDs		F5H6X3 Q96JH8	P15976
PDB IDs		1UM1 3EC8
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Dephosphorylation Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Regulation Of Metabolic Process Basophil Differentiation Eosinophil Fate Commitment G2/M Transition Of Mitotic Cell Cycle Eosinophil Differentiation Transcriptional Activation By Promoter-enhancer Looping Regulation Of Dephosphorylation Cellular Response To Hormone Stimulus Insulin Receptor Signaling Pathway Regulation Of Definitive Erythrocyte Differentiation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Protein Dephosphorylation Alveolar Secondary Septum Development Negative Regulation Of Protein Transport Axonogenesis Involved In Innervation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Phosphorus Metabolic Process Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Maintenance Of DNA Methylation Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Chondrocyte Proliferation Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway MAPK Cascade Cellular Response To Thyroid Hormone Stimulus Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Intracellular Signal Transduction Regulation Of Centriole Replication Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Regulation Of Cellular Process Mitotic Cell Cycle Phase Transition Positive Regulation Of Phosphorylation Cell Cycle Phase Transition	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Gene Expression RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Biosynthetic Process Nucleosome Disassembly Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Developmental Process Chromatin Organization Regulation Of Cellular Process Anatomical Structure Development Chromatin Remodeling Myeloid Cell Differentiation Chromatin Modification Cell Differentiation Multicellular Organismal Development Embryonic Organ Development Hemopoiesis Chromosome Organization Megakaryocyte Differentiation Immune System Development
Tagcloud ?		adhesion adhesiveness associates concurrent dynamics effector effectors emerging focal gtpase influences inside integrin kif14 kinesin mediate microtubules migration negatively optimal pdz polarity rap rap1 reach regulates spreading tethering thereby	alls blasts cd3 cd45 comprised deregulation disrupted enable exploited fused haemopoietic immunocytochemical leukaemia leukaemic lymphoblastic lymphoid monocytes morphologically ordinately origin precursors rearrangement resembled sil tal tal1 transcripts unexplained unidentified
Tagcloud (Difference) ?		adhesion adhesiveness associates concurrent dynamics effector effectors emerging focal gtpase influences inside integrin kif14 kinesin mediate microtubules migration negatively optimal pdz polarity rap rap1 reach regulates spreading tethering thereby	alls blasts cd3 cd45 comprised deregulation disrupted enable exploited fused haemopoietic immunocytochemical leukaemia leukaemic lymphoblastic lymphoid monocytes morphologically ordinately origin precursors rearrangement resembled sil tal tal1 transcripts unexplained unidentified
Tagcloud (Intersection) ?