CETN2 and SFI1

Number of citations of the paper that reports this interaction (PubMedID 14504268)
72

Data Source:
HPRD (in vitro)

		CETN2	SFI1
Description		centrin 2	SFI1 centrin binding protein
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex Glial Cell Projection 9+2 Motile Cilium	Cytoplasm Centriole Cytosol Cytoskeleton
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding Metal Ion Binding	Protein Binding Phosphatase Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle DNA Repair Nucleotide-excision Repair DNA Damage Response Centriole Replication Spermatogenesis Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division
Pathways		Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Serum alkaline phosphatase levels ( 33339817)	A body shape index ( 34021172) Age-related hearing impairment ( 24939585) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Fish- and plant-related diet ( 32066663) Lymphocyte count ( 32888494) Metabolite levels ( 23823483) Neutrophil percentage of white cells ( 32888494) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Type 2 diabetes ( 31118516)
Interacting Genes		7 interacting genes: ARSA CCP110 PNMA5 PRMT6 SFI1 UBC XPC	15 interacting genes: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH GOLGA2 KRT19 LPXN MAD2L2 MDFI PPP1CA RADIL RBPMS SERTAD1
Entrez ID		1069	9814
HPRD ID		02051	11550
Ensembl ID		ENSG00000147400	ENSG00000198089
Uniprot IDs		P41208	A8K8P3
PDB IDs		1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH 8EBS 8EBT 8EBV 8EBW 8EBX 8J07	2K2I
Enriched GO Terms of Interacting Partners?			Microtubule Organizing Center Organization Telomere Maintenance In Response To DNA Damage Centriole Replication Cell Differentiation Involved In Embryonic Placenta Development Centriole Assembly Centriole Microtubule Nucleation Microtubule Cytoskeleton Organization Cell Division
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