CEP57 and GCC1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP57	GCC1
Gene Name		centrosomal protein 57kDa	GRIP and coiled-coil domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Microtubule Microtubule Cytoskeleton	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane
	Molecular Function	Protein Binding Microtubule Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Gamma-tubulin Binding	Protein Binding
	Biological Process	Protein Import Into Nucleus, Translocation G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Spermatid Development Fibroblast Growth Factor Receptor Signaling Pathway Microtubule Anchoring Protein Homooligomerization	Protein Targeting To Golgi
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Type 2 diabetes ( 22158537)
Protein-Protein Interactions		15 interactors: APP CEP63 CTAGE5 FGF2 GCC1 KRT13 KRT15 KRT31 KRT40 MAGEA2B MEGF10 MYC RALBP1 TFIP11 UIMC1	36 interactors: ABI2 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC85B CEP57 CEP70 COIL CPSF7 DNAJA3 FBF1 GLI1 GOLGA2 GTF2I IKBKG ITSN1 KIAA0753 KIAA1217 LZTS2 MCRS1 NAB2 NAV1 NECAB2 NINL OIP5 PAK7 SMARCD1 TFIP11 TRIM29 USHBP1 ZNF276
Entrez ID		9702	79571
HPRD ID		16261	07599
Ensembl ID		ENSG00000166037	ENSG00000179562
Uniprot IDs		F5GYW0 Q86XR8	A4D0Z4 Q96CN9
PDB IDs		4L0R
Enriched GO Terms of Interacting Partners?		Response To Radiation Positive Regulation Of Catalytic Activity Tissue Development Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Spliceosomal Complex Disassembly Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Satellite Cell Proliferation Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Response To DNA Damage Stimulus Ureteric Bud Morphogenesis Nephron Morphogenesis Developmental Process Renal Tubule Morphogenesis Skeletal Muscle Cell Proliferation Synaptic Growth At Neuromuscular Junction Skeletal Muscle Satellite Cell Activation Fibroblast Apoptotic Process Regulation Of Catalytic Activity Renal Tubule Development Cellular Metal Ion Homeostasis Positive Regulation Of Metabolic Process Kidney Morphogenesis Histone H2A K63-linked Deubiquitination Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Collateral Sprouting In Absence Of Injury Cellular Cation Homeostasis Cellular Ion Homeostasis Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Metal Ion Homeostasis Positive Regulation Of Hydrolase Activity Cell Recognition Regulation Of Response To DNA Damage Stimulus Mesonephros Development Anatomical Structure Development Collateral Sprouting Axon Midline Choice Point Recognition Epithelium Development Regulation Of Striated Muscle Tissue Development Response To Abiotic Stimulus Notch Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Nephron Development Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Cellular Chemical Homeostasis Positive Regulation Of Peptidase Activity Transition Metal Ion Homeostasis	Apoptotic Process Programmed Cell Death Cell Death Death Organelle Organization Transcription, DNA-templated RNA Metabolic Process Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Intracellular Signal Transduction Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Anatomical Structure Development Developmental Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Toxin Metabolic Process Negative Regulation Of Cell Death Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase III Promoter Nitrogen Compound Metabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Cell Communication Positive Regulation Vascular Endothelial Growth Factor Production Signal Transduction Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death System Development Multicellular Organismal Development Cellular Process NIK/NF-kappaB Signaling Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Biosynthetic Process Cell Cycle Positive Regulation Of Histone H4-K20 Methylation Spliceosomal Complex Disassembly Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Monoubiquitination Positive Regulation Of Protein K48-linked Ubiquitination
Tagcloud ?		accumulation associates cdk4 contributing cyclin d1 detail drives exit hinders import inactivation juxtanuclear maintain microtubule neoplastic nucleocytoplasmic prb prevents proliferating proper quiescence quiescent termed tlk trafficking translokin turn undue
Tagcloud (Difference) ?		accumulation associates cdk4 contributing cyclin d1 detail drives exit hinders import inactivation juxtanuclear maintain microtubule neoplastic nucleocytoplasmic prb prevents proliferating proper quiescence quiescent termed tlk trafficking translokin turn undue
Tagcloud (Intersection) ?