CD69 and TSPO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD69	TSPO2
Description		CD69 molecule	translocator protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Protein-containing Complex	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Organelle Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Molecular Sequestering Activity	Protein Binding Cholesterol Binding 5-aminolevulinic Acid Transmembrane Transporter Activity
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway Cellular Response To Xenobiotic Stimulus T Cell Migration Negative Regulation Of T-helper 17 Cell Lineage Commitment Negative Regulation Of T Cell Migration	Intracellular Cholesterol Transport Lipid Droplet Organization Enucleate Erythrocyte Differentiation Import Across Plasma Membrane 5-aminolevulinic Acid Import Across Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Lymphocyte count ( 27863252 29403010 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 24076602) Neutrophil percentage of white cells ( 27863252 32888494) Type 1 diabetes ( 19430480 25751624) White blood cell count ( 32888494)	Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866)
Interacting Genes		14 interacting genes: ATP6V0C BRICD5 CLDN1 EBP MAL NINJ2 PMP22 RPRM SLC35B2 SMARCB1 STRIT1 TMEM190 TSPO2 UPK1B	62 interacting genes: AHNAK2 AQP6 ARL13B ASGR2 ASZ1 BIK CD53 CD69 CD79A CERS4 CLDN4 CNR2 COL4A5 CPLX4 CREB3L1 DKK4 EBP EFNA5 EMP1 ERGIC3 ERP29 FCER1G FCGR1A FFAR2 FKBP7 FNDC9 FXYD3 GGT7 GJB5 GPR152 GPR42 GPX8 IGFBP5 KCNJ6 KLRC1 LRRC59 MAL MARCHF2 MFF MFSD6 MS4A1 PDZK1IP1 PLEKHO1 PSCA RELL2 RETREG3 RPRM SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35H1 SLC41A3 SLC7A1 SPAG4 STOM SYT2 TMEM140 TMEM54 TMEM80 VSIR
Entrez ID		969	222642
HPRD ID		00119	16569
Ensembl ID		ENSG00000110848	ENSG00000112212
Uniprot IDs		Q07108 Q53ZX0	Q5TGU0
PDB IDs		1E87 1E8I 1FM5 3CCK 3HUP 8G94
Enriched GO Terms of Interacting Partners?		Membrane Protein Localization To Paranode Region Of Axon Cellular Developmental Process Protein Insertion Into Plasma Membrane Myelination Apical Plasma Membrane Axon Ensheathment Membrane Raft Polarization Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Membrane Destabilizing Activity Cholesterol Binding Compact Myelin Positive Regulation Of Glucose Mediated Signaling Pathway Germ Cell Nucleus Regulation Of Glucose Mediated Signaling Pathway Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Apical Plasma Membrane Urothelial Plaque Cellular Response To Butyrate Response To Butyrate Xenobiotic Transport Across Blood-nerve Barrier Cellular Response To Lead Ion Response To Interleukin-18 Establishment Of Blood-nerve Barrier Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Steroid Delta-isomerase Activity Cholestenol Delta-isomerase Activity Inner Acrosomal Membrane 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transport 5'-adenylyl Sulfate Transmembrane Transport 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction	Membrane Plasma Membrane Protein Binding Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I External Side Of Plasma Membrane Positive Regulation Of Type III Hypersensitivity Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Type IIa Hypersensitivity Positive Regulation Of Acute Inflammatory Response Bile Acid:sodium Symporter Activity Transmembrane Transport Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Hypersensitivity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Antigen Processing And Presentation Of Exogenous Peptide Antigen Sodium Ion Transport Regulation Of Acute Inflammatory Response Antigen Processing And Presentation Of Exogenous Antigen Immune Response-regulating Signaling Pathway Serotonin Transport
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