CD69 and RPRM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD69	RPRM
Description		CD69 molecule	reprimo, TP53 dependent G2 arrest mediator homolog
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Protein-containing Complex	Cytoplasm Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Molecular Sequestering Activity	Protein Binding
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway Cellular Response To Xenobiotic Stimulus T Cell Migration Negative Regulation Of T-helper 17 Cell Lineage Commitment Negative Regulation Of T Cell Migration	Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Lymphocyte count ( 27863252 29403010 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 24076602) Neutrophil percentage of white cells ( 27863252 32888494) Type 1 diabetes ( 19430480 25751624) White blood cell count ( 32888494)	Anti-saccade response ( 29064472) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		14 interacting genes: ATP6V0C BRICD5 CLDN1 EBP MAL NINJ2 PMP22 RPRM SLC35B2 SMARCB1 STRIT1 TMEM190 TSPO2 UPK1B	80 interacting genes: ADGRG3 AMIGO1 AQP6 ARFIP1 ASGR2 BNIP3 BSCL2 BTNL9 C16orf54 CD33 CD53 CD69 CLDN5 CLDN7 CLDN9 CLEC17A CLEC2D COQ8A CREB3 CXorf66 EHHADH EMP1 FAM209A FAM210B FATE1 FBXL19 FCGR1A FFAR2 FGD2 FKBP7 FNDC9 GAD2 GJA5 GJB3 GJB5 GNG13 GPR37L1 GPR42 GPX8 HHLA2 HIP1 HSD17B13 KCNJ6 LAPTM5 LHFPL5 LMNA LPAR6 MPP1 MS4A4A MTIF3 OPRD1 OPRM1 PBX3 PDZK1IP1 PLEKHF2 PNKP SCAND1 SDCBP SENP2 SLC18A1 SLC38A1 SMIM3 SNX11 SNX12 SNX3 SPACA1 SPCS1 STOM SUSD3 SYT16 TM4SF18 TMEM106C TMEM237 TMEM79 TMEM80 TMEM86B TSPO2 TTPA WDFY2 ZDHHC22
Entrez ID		969	56475
HPRD ID		00119	18002
Ensembl ID		ENSG00000110848	ENSG00000177519
Uniprot IDs		Q07108 Q53ZX0	Q9NS64
PDB IDs		1E87 1E8I 1FM5 3CCK 3HUP 8G94
Enriched GO Terms of Interacting Partners?		Membrane Protein Localization To Paranode Region Of Axon Cellular Developmental Process Protein Insertion Into Plasma Membrane Myelination Apical Plasma Membrane Axon Ensheathment Membrane Raft Polarization Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Membrane Destabilizing Activity Cholesterol Binding Compact Myelin Positive Regulation Of Glucose Mediated Signaling Pathway Germ Cell Nucleus Regulation Of Glucose Mediated Signaling Pathway Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Apical Plasma Membrane Urothelial Plaque Cellular Response To Butyrate Response To Butyrate Xenobiotic Transport Across Blood-nerve Barrier Cellular Response To Lead Ion Response To Interleukin-18 Establishment Of Blood-nerve Barrier Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Steroid Delta-isomerase Activity Cholestenol Delta-isomerase Activity Inner Acrosomal Membrane 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transport 5'-adenylyl Sulfate Transmembrane Transport 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction	Membrane Protein Binding Plasma Membrane Negative Regulation Of Early Endosome To Late Endosome Transport Connexin Complex Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Gap Junction Channel Activity Endoplasmic Reticulum Phosphatidylinositol Binding External Side Of Plasma Membrane Gap Junction Gamma-aminobutyric Acid Biosynthetic Process Phosphatidylinositol Phosphate Binding Late Endosome To Golgi Transport
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