CD69 and SLC35B2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD69	SLC35B2
Description		CD69 molecule	solute carrier family 35 member B2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Protein-containing Complex	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Molecular Sequestering Activity	Protein Binding Antiporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway Cellular Response To Xenobiotic Stimulus T Cell Migration Negative Regulation Of T-helper 17 Cell Lineage Commitment Negative Regulation Of T Cell Migration	Positive Regulation Of Canonical NF-kappaB Signal Transduction 3'-phosphoadenosine 5'-phosphosulfate Transport Chondroitin Sulfate Proteoglycan Biosynthetic Process Transmembrane Transport 5'-adenylyl Sulfate Transmembrane Transport 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport
Pathways			Transport and metabolism of PAPS Transport of nucleotide sugars
Drugs
Diseases
GWAS		Lymphocyte count ( 27863252 29403010 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 24076602) Neutrophil percentage of white cells ( 27863252 32888494) Type 1 diabetes ( 19430480 25751624) White blood cell count ( 32888494)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		14 interacting genes: ATP6V0C BRICD5 CLDN1 EBP MAL NINJ2 PMP22 RPRM SLC35B2 SMARCB1 STRIT1 TMEM190 TSPO2 UPK1B	12 interacting genes: AQP6 ASGR2 CD69 CLDN15 CREB3L1 CYB5R3 ERGIC3 LMNA SHISAL1 TEX29 TMEM237 TMEM248
Entrez ID		969	347734
HPRD ID		00119	11576
Ensembl ID		ENSG00000110848	ENSG00000157593
Uniprot IDs		Q07108 Q53ZX0	Q8TB61
PDB IDs		1E87 1E8I 1FM5 3CCK 3HUP 8G94
Enriched GO Terms of Interacting Partners?		Membrane Protein Localization To Paranode Region Of Axon Cellular Developmental Process Protein Insertion Into Plasma Membrane Myelination Apical Plasma Membrane Axon Ensheathment Membrane Raft Polarization Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Membrane Destabilizing Activity Cholesterol Binding Compact Myelin Positive Regulation Of Glucose Mediated Signaling Pathway Germ Cell Nucleus Regulation Of Glucose Mediated Signaling Pathway Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Apical Plasma Membrane Urothelial Plaque Cellular Response To Butyrate Response To Butyrate Xenobiotic Transport Across Blood-nerve Barrier Cellular Response To Lead Ion Response To Interleukin-18 Establishment Of Blood-nerve Barrier Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Steroid Delta-isomerase Activity Cholestenol Delta-isomerase Activity Inner Acrosomal Membrane 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transport 5'-adenylyl Sulfate Transmembrane Transport 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction
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