KLC4 and SERTAD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KLC4	SERTAD1
Description		kinesin light chain 4	SERTA domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Kinesin Complex Microtubule	Nucleus Cytoplasm Sarcoplasm
	Molecular Function	Protein Binding Kinesin Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Microtubule-based Movement	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693)	Monocyte percentage of white cells ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		32 interacting genes: ABI3 AKAP9 APP CASK CEP57 CEP57L1 COIL DDX6 KATNAL1 KPNA2 KRT13 KRT15 KRT16 KRT31 KRT33B KRT34 MEOX2 NDEL1 NECAB2 PCM1 PDE4DIP PKP2 PRC1 RBM14 SERTAD1 SLC16A9 TADA2A TSC1 USHBP1 YWHAE YWHAZ ZNF343	56 interacting genes: ADCY1 AIRIM ASB8 ATG12 ATXN7L3 BANF2 CCND2 CDK4 CDKN2A CHAF1A CHURC1 CIB3 CINP CKS1B COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAAP20 FAH FNDC11 FXR1 GLYCTK HIVEP1 HSPB1 KAT2B KLC4 KLHL42 MVP P4HA3 PATE1 PBX4 PICK1 PIH1D2 POT1 PRDM4 PSORS1C2 RBX1 RCHY1 ROPN1 SEC14L4 SETD7 SFI1 SMAD3 SPEN SSX7 STAT5B SUPT7L TGM2 TLR4 TRIM28 TSC1 XIAP ZNF410
Entrez ID		89953	29950
HPRD ID		13932	15326
Ensembl ID		ENSG00000137171	ENSG00000197019
Uniprot IDs		Q9NSK0	Q53GC0 Q9UHV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Cytoskeleton Organization Intermediate Filament Cytoskeleton Keratin Filament Organelle Organization Structural Molecule Activity Tissue Morphogenesis Microtubule-based Process Morphogenesis Of An Epithelium Anatomical Structure Morphogenesis Phosphoserine Residue Binding Identical Protein Binding Regulation Of Heart Rate By Cardiac Conduction Epithelial Cell Differentiation Cardiac Conduction Microtubule Binding Transmembrane Transporter Binding Epidermis Development Neuron Migration Microtubule Cytoskeleton Organization Centrosome Cytoplasmic Microtubule Organization Hair Cycle Protein Binding Molecular Adaptor Activity Microtubule Regulation Of Golgi Organization Microtubule Organizing Center Organization Developmental Process Microtubule Organizing Center Structural Constituent Of Cytoskeleton Regulation Of Heart Rate Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Blood Circulation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Localization Cytosol Concave Side Of Sperm Head Maintenance Of Protein Localization At Cell Tip Memory T Cell Differentiation Positive Regulation Of Microtubule Polymerization	N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Macromolecule Biosynthetic Process P53 Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress RNA Polymerase II-specific DNA-binding Transcription Factor Binding Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Histone H3K27 Acetyltransferase Activity Regulation Of DNA Repair Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Protein Localization To Nucleus Protein Binding Cellular Response To Stress Cyclin D2-CDK4 Complex Acetyltransferase Activity Histone H3K18 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Nucleus Protein Modification Process DNA Damage Response Canonical NF-kappaB Signal Transduction Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Histone Acetyltransferase Complex Transcription Coregulator Activity SAGA Complex Protein-lysine-acetyltransferase Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Stabilization Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Chromatin Regulation Of Protein Localization To Nucleus Chromatin Binding Histone Acetyltransferase Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Chromo Shadow Domain Binding Protein Acetylation Cellular Response To Nutrient Levels Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Histone H3 Acetyltransferase Activity Internal Peptidyl-lysine Acetylation Positive Regulation Of Protein Import Into Nucleus
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