CCDC198 and FKBP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC198	FKBP6
Description		coiled-coil domain containing 198	FKBP prolyl isomerase family member 6 (inactive)
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cytoplasmic Vesicle	Synaptonemal Complex Fibrillar Center Nucleus Cytoplasm Cytosol Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding
	Biological Process	Energy Homeostasis	Protein Folding Spermatogenesis Cell Differentiation Regulatory NcRNA-mediated Gene Silencing PiRNA Processing Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle Transposable Element Silencing By PiRNA-mediated DNA Methylation
Pathways			Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS			Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		27 interacting genes: CBY2 FAM9B FHL2 FHL3 FKBP6 GOLGA2 GOPC HOOK2 HSF2BP IQGAP3 KIFC3 KRT31 KRT34 KRT40 LZTS2 MDFI MTUS2 PDE4DIP PFDN5 PNMA1 SIAH1 SMAD3 SSX2IP TEX11 TRAF1 TRAF2 TRIM27	38 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CFTR CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 RAB11FIP2 RNF4 SAXO4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655
Entrez ID		55195	8468
HPRD ID		12628	05326
Ensembl ID		ENSG00000100557	ENSG00000077800
Uniprot IDs		B7ZL43 E9PSE9 F5GWJ3 Q05C89 Q9NVL8	O75344
PDB IDs			3B7X
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Supramolecular Fiber Organization Synaptonemal Complex Cytoplasm Organelle Organization Cytoskeleton Centrosome Cycle Cytoskeleton Organization Structural Constituent Of Skin Epidermis Thioesterase Binding Microtubule Intermediate Filament Organization Microtubule Organizing Center Organization Developmental Process Involved In Reproduction Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Centrosome Microtubule Binding Reproductive Process BHLH Transcription Factor Binding Meiotic Cell Cycle Protein Binding Microtubule-based Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding RNA Polymerase III Assembly RNA Polymerase I Assembly Tumor Necrosis Factor Receptor Binding TORC2 Complex Disassembly Meiotic Gene Conversion Negative Regulation Of Anion Channel Activity Primary Ureteric Bud Growth Myosin VI Light Chain Binding Morphogenesis Of An Epithelium Signal Transduction Involved In Regulation Of Gene Expression Intermediate Filament	Shelterin Complex Telomere Assembly Meiotic DNA Double-strand Break Formation Protein Binding Regulation Of Telomere Maintenance Via Telomerase Nuclear Telomere Cap Complex Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Localization To Chromosome, Telomeric Region
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