SEC24C and WIPF1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SEC24C	WIPF1
Gene Name		SEC24 family member C	WAS/WASL interacting protein family, member 1
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Perinuclear Region Of Cytoplasm	Ruffle Cytosol Actin Filament Actin Cytoskeleton Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Molecular_function Protein Binding Zinc Ion Binding	Actin Binding Protein Binding Profilin Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process COPII Vesicle Coating Membrane Organization	Protein Complex Assembly Actin Polymerization Or Depolymerization Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Response To Other Organism
Pathways		Diseases of glycosylation Metabolism of lipids and lipoproteins Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Antigen Presentation: Folding, assembly and peptide loading of class I MHC Defective MOGS causes MOGS-CDG (CDG-2b) Regulation of cholesterol biosynthesis by SREBP (SREBF) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Adaptive Immune System	Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP FBXO7 MOS SEC23A SEC23B SPP1 WIPF1	22 interactors: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 PRKCQ PRPF40A SEC24C WAS WASL WBP4 WWP2 ZAP70
Entrez ID		9632	7456
HPRD ID		06217	03835
Ensembl ID		ENSG00000176986	ENSG00000115935
Uniprot IDs		E7EP00 P53992	O43516 Q2YDC4
PDB IDs		3EH2	2A41
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Phase Transition Establishment Of Localization In Cell Cellular Localization Regulation Of Cell Cycle Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle ER To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Intracellular Transport Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Synaptic Growth At Neuromuscular Junction Cytoplasmic Transport Collateral Sprouting In Absence Of Injury Negative Regulation Of Cell Differentiation Regulation Of Protein Kinase Activity Negative Regulation Of Meiotic Cell Cycle Phase Transition Regulation Of Kinase Activity Negative Regulation Of Neuron Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Establishment Of Meiotic Spindle Localization Regulation Of Mitotic Cell Cycle Phase Transition Intracellular Protein Transport Regulation Of Cell Cycle Immune System Process Negative Regulation Of Collateral Sprouting Axon Choice Point Recognition Negative Regulation Of Axon Regeneration Golgi Vesicle Transport Reproduction Neuron Remodeling Regulation Of Protein Phosphorylation Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Meiotic Spindle Organization Establishment Of Organelle Localization Negative Regulation Of Cell Development Positive Regulation Of Bone Resorption Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Phosphorylation Defense Response Cellular Protein Localization Regulation Of Axon Regeneration Cellular Copper Ion Homeostasis Transport COPII Vesicle Coating Regulation Of Mitotic Cell Cycle	Immune Response-activating Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Locomotion Immune Response-regulating Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Immune Response Phagocytosis Endocytosis Actin Filament Organization Regulation Of Cytoskeleton Organization Innate Immune Response Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Cell Migration Actin Cytoskeleton Organization Positive Regulation Of Actin Nucleation Regulation Of Immune Response Axon Guidance Cell Motility Positive Regulation Of Immune System Process Positive Regulation Of Organelle Organization Actin Filament-based Process Regulation Of Actin Filament-based Process Neuron Projection Morphogenesis Neuron Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Vesicle-mediated Transport Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Organization Neuron Differentiation Axonogenesis Cell Projection Organization Cell Projection Morphogenesis Axon Development Cell Part Morphogenesis Actin Polymerization Or Depolymerization Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Organelle Organization Immune System Process Immune Response
Tagcloud ?		cargoes coated compensation considerably copii deficiency dispensable embryonic exhibiting fourth golgi haploinsufficient hepatocytes homozygous hypocholesterolemic lethality mammals nascent null paralog paralogs phenotypically tube vertebrate vesicles
Tagcloud (Difference) ?		cargoes coated compensation considerably copii deficiency dispensable embryonic exhibiting fourth golgi haploinsufficient hepatocytes homozygous hypocholesterolemic lethality mammals nascent null paralog paralogs phenotypically tube vertebrate vesicles
Tagcloud (Intersection) ?