SEC24C and SEC23B

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (biochemical)
HPRD (two hybrid)

		SEC24C	SEC23B
Gene Name		SEC24 family member C	Sec23 homolog B (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Perinuclear Region Of Cytoplasm	Golgi Membrane Endoplasmic Reticulum Membrane Endomembrane System Membrane COPII Vesicle Coat Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding Zinc Ion Binding	Zinc Ion Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process COPII Vesicle Coating Membrane Organization	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle-mediated Transport
Pathways		Diseases of glycosylation Metabolism of lipids and lipoproteins Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Antigen Presentation: Folding, assembly and peptide loading of class I MHC Defective MOGS causes MOGS-CDG (CDG-2b) Regulation of cholesterol biosynthesis by SREBP (SREBF) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP FBXO7 MOS SEC23A SEC23B SPP1 WIPF1	18 interactors: CPSF7 DTX2 FATE1 GALNT1 HOXA3 KDELR1 MAN2A1 PRRC1 SEC24C SEC24D SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 UGT1A1
Entrez ID		9632	10483
HPRD ID		06217	11543
Ensembl ID		ENSG00000176986	ENSG00000101310
Uniprot IDs		E7EP00 P53992	B4DJW8 Q15437
PDB IDs		3EH2
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Phase Transition Establishment Of Localization In Cell Cellular Localization Regulation Of Cell Cycle Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle ER To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Intracellular Transport Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Synaptic Growth At Neuromuscular Junction Cytoplasmic Transport Collateral Sprouting In Absence Of Injury Negative Regulation Of Cell Differentiation Regulation Of Protein Kinase Activity Negative Regulation Of Meiotic Cell Cycle Phase Transition Regulation Of Kinase Activity Negative Regulation Of Neuron Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Establishment Of Meiotic Spindle Localization Regulation Of Mitotic Cell Cycle Phase Transition Intracellular Protein Transport Regulation Of Cell Cycle Immune System Process Negative Regulation Of Collateral Sprouting Axon Choice Point Recognition Negative Regulation Of Axon Regeneration Golgi Vesicle Transport Reproduction Neuron Remodeling Regulation Of Protein Phosphorylation Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Meiotic Spindle Organization Establishment Of Organelle Localization Negative Regulation Of Cell Development Positive Regulation Of Bone Resorption Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Phosphorylation Defense Response Cellular Protein Localization Regulation Of Axon Regeneration Cellular Copper Ion Homeostasis Transport COPII Vesicle Coating Regulation Of Mitotic Cell Cycle	Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting COPII Vesicle Coating COPII-coated Vesicle Budding Membrane Budding COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization ER To Golgi Vesicle-mediated Transport Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Post-translational Protein Modification Cargo Loading Into Vesicle Golgi Organization Protein N-linked Glycosylation Via Asparagine Protein Glycosylation Macromolecule Glycosylation Protein N-linked Glycosylation Glycosylation Positive Regulation Of Viral Genome Replication Glycoprotein Biosynthetic Process Glycoprotein Metabolic Process Membrane Organization Protein Transport Vesicle-mediated Transport Intracellular Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Complex Assembly Organelle Organization Negative Regulation Of Viral Genome Replication Carbohydrate Metabolic Process Nuclear Speck Organization Biphenyl Catabolic Process Bilirubin Conjugation Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Transport Cellular Component Assembly Protein Localization Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Establishment Of Localization In Cell Cellular Protein Localization RNA Splicing
Tagcloud ?		cargoes coated compensation considerably copii deficiency dispensable embryonic exhibiting fourth golgi haploinsufficient hepatocytes homozygous hypocholesterolemic lethality mammals nascent null paralog paralogs phenotypically tube vertebrate vesicles	aflatoxin biogenesis btf3 calreticulin compartments confer dissected dynactin eef immunoblot nodules nucleolin nucleophosmin oncomine p450 participates peptidase pgrmc1 pur ribosome rough sec13 subcellular ter traffic transitional tripeptidyl unexpectedly usp10
Tagcloud (Difference) ?		cargoes coated compensation considerably copii deficiency dispensable embryonic exhibiting fourth golgi haploinsufficient hepatocytes homozygous hypocholesterolemic lethality mammals nascent null paralog paralogs phenotypically tube vertebrate vesicles	aflatoxin biogenesis btf3 calreticulin compartments confer dissected dynactin eef immunoblot nodules nucleolin nucleophosmin oncomine p450 participates peptidase pgrmc1 pur ribosome rough sec13 subcellular ter traffic transitional tripeptidyl unexpectedly usp10
Tagcloud (Intersection) ?