CYTIP and CYTH1

Number of citations of the paper that reports this interaction (PMID 11867758)
13

Data Source:
HPRD (two hybrid, in vitro)

		CYTIP	CYTH1
Gene Name		cytohesin 1 interacting protein	cytohesin 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Early Endosome Cell Cortex	Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Binding	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Regulation Of Cell Adhesion	Vesicle-mediated Transport Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity Establishment Of Epithelial Cell Polarity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CYTH1 CYTH2 CYTH3 SOCS1	12 interactors: ACTA1 ARF1 ARF6 ARFRP1 ARR3 CYTIP GNAQ IPCEF1 ITGB2 ITSN1 PRKCD TRIM23
Entrez ID		9595	9267
HPRD ID		09192	01630
Ensembl ID		ENSG00000115165	ENSG00000108669
Uniprot IDs		O60759	Q15438
PDB IDs		2Z17	1BC9 4A4P
Enriched GO Terms of Interacting Partners?		Regulation Of ARF Protein Signal Transduction Establishment Of Epithelial Cell Polarity Regulation Of Intracellular Signal Transduction Regulation Of Cell Adhesion Regulation Of Ras Protein Signal Transduction Regulation Of Catalytic Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Establishment Of Cell Polarity Regulation Of GTPase Activity Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of Hydrolase Activity Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Catalytic Activity Regulation Of Interferon-gamma-mediated Signaling Pathway Negative Regulation Of JAK-STAT Cascade JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Response To Interferon-gamma Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Negative Regulation Of Insulin Receptor Signaling Pathway Response To Growth Hormone Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Peptidyl-tyrosine Phosphorylation JAK-STAT Cascade Regulation Of Metabolic Process Cellular Response To Amino Acid Stimulus Positive Regulation Of Metabolic Process Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus	Small GTPase Mediated Signal Transduction Vesicle-mediated Transport Response To Stimulus Cellular Response To Stimulus Signal Transduction Intracellular Signal Transduction Signaling Regulation Of Filopodium Assembly Regulation Of Phosphorylation Cell Communication Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipase Activity Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Post-Golgi Vesicle-mediated Transport Positive Regulation Of Lipase Activity Regulation Of Actin Filament-based Process Protein Stabilization Positive Regulation Of Phospholipid Catabolic Process Skeletal Muscle Fiber Adaptation Apoptotic Process Blood Coagulation Hemostasis Programmed Cell Death Lymphocyte Proliferation Cell Death Mononuclear Cell Proliferation Death Regulation Of Protein Phosphorylation Interleukin-10 Production Regulation Of Cell Projection Assembly Leukocyte Proliferation Regulation Of Cytoskeleton Organization Negative Regulation Of Filopodium Assembly Regulation Of Protein Stability Interleukin-12 Production Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Body Fluid Levels Positive Regulation Of Ceramide Biosynthetic Process Wound Healing Skeletal Muscle Thin Filament Assembly Regulation Of Actin Filament Polymerization Embryonic Morphogenesis Endocytosis
Tagcloud ?		analyzing archetypical branch ccrcc chemotactic cxcr4 cytohesin driven empower enables epigenetically expanded exploit focusing h3k27me3 hif hifs hippel initiating lindau lys27 output polycomb prc2 repressive subpopulations trimethylation vhl von
Tagcloud (Difference) ?		analyzing archetypical branch ccrcc chemotactic cxcr4 cytohesin driven empower enables epigenetically expanded exploit focusing h3k27me3 hif hifs hippel initiating lindau lys27 output polycomb prc2 repressive subpopulations trimethylation vhl von
Tagcloud (Intersection) ?