CYTIP and CYTH2

Number of citations of the paper that reports this interaction (PMID 12606567)
11

Data Source:
HPRD (in vitro)

		CYTIP	CYTH2
Gene Name		cytohesin 1 interacting protein	cytohesin 2
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Early Endosome Cell Cortex	Cytoplasm Trans-Golgi Network Plasma Membrane Membrane
	Molecular Function	Protein Binding	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Regulation Of Cell Adhesion	Endocytosis Vesicle-mediated Transport Actin Cytoskeleton Organization Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CYTH1 CYTH2 CYTH3 SOCS1	21 interactors: ADORA2A APC ARF1 ARF6 ARFGAP1 ARRB1 ARRB2 ATP6V0A2 CCDC120 CUX1 CYTIP DYT10 GNAQ IPCEF1 ITGB2 MAPK6 PNPLA2 PRKCA PRKCB PRKCG TRIM23
Entrez ID		9595	9266
HPRD ID		09192	03925
Ensembl ID		ENSG00000115165	ENSG00000105443
Uniprot IDs		O60759	Q99418
PDB IDs		2Z17	1PBV 1R8M 1R8Q 1R8S 1S9D
Enriched GO Terms of Interacting Partners?		Regulation Of ARF Protein Signal Transduction Establishment Of Epithelial Cell Polarity Regulation Of Intracellular Signal Transduction Regulation Of Cell Adhesion Regulation Of Ras Protein Signal Transduction Regulation Of Catalytic Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Establishment Of Cell Polarity Regulation Of GTPase Activity Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of Hydrolase Activity Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Catalytic Activity Regulation Of Interferon-gamma-mediated Signaling Pathway Negative Regulation Of JAK-STAT Cascade JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Response To Interferon-gamma Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Negative Regulation Of Insulin Receptor Signaling Pathway Response To Growth Hormone Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Peptidyl-tyrosine Phosphorylation JAK-STAT Cascade Regulation Of Metabolic Process Cellular Response To Amino Acid Stimulus Positive Regulation Of Metabolic Process Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus	Blood Coagulation Hemostasis Platelet Activation Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Signal Transduction Apoptotic Process Programmed Cell Death Signaling Histone H3-T6 Phosphorylation Cell Death Death Cell Communication Positive Regulation Of Metabolic Process Regulation Of Receptor Internalization Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Activation Of Phospholipase C Activity Regulation Of Protein Phosphorylation Response To Stimulus Positive Regulation Of Phospholipase C Activity Regulation Of Endocytosis Response To Stress Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phospholipase Activity Regulation Of Catalytic Activity Membrane Organization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Regulation Of Phosphorylation Regulation Of Cellular Process Cell Surface Receptor Signaling Pathway Regulation Of Phospholipase Activity G-protein Coupled Receptor Internalization Negative Regulation Of Protein Metabolic Process Positive Regulation Of Lipase Activity Enzyme Linked Receptor Protein Signaling Pathway Golgi Vesicle Transport Protein Localization Golgi Vesicle Budding Positive Regulation Of Cellular Metabolic Process Protein Transport Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Glucose Transport Vesicle-mediated Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Establishment Of Protein Localization
Tagcloud ?		analyzing archetypical branch ccrcc chemotactic cxcr4 cytohesin driven empower enables epigenetically expanded exploit focusing h3k27me3 hif hifs hippel initiating lindau lys27 output polycomb prc2 repressive subpopulations trimethylation vhl von
Tagcloud (Difference) ?		analyzing archetypical branch ccrcc chemotactic cxcr4 cytohesin driven empower enables epigenetically expanded exploit focusing h3k27me3 hif hifs hippel initiating lindau lys27 output polycomb prc2 repressive subpopulations trimethylation vhl von
Tagcloud (Intersection) ?