GOSR2 and STX6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GOSR2	STX6
Gene Name		golgi SNAP receptor complex member 2	syntaxin 6
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack ER To Golgi Transport Vesicle Membrane Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane	Golgi Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	SNARE Binding Transporter Activity SNAP Receptor Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Retrograde Transport, Endosome To Golgi Cellular Protein Metabolic Process Vesicle Fusion With Golgi Apparatus Membrane Fusion	Intracellular Protein Transport Vesicle Fusion Endosome Organization Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Golgi Ribbon Formation
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Systolic blood pressure ( 21909115) Ventricular conduction ( 21076409)	Progressive supranuclear palsy ( 21685912)
Protein-Protein Interactions		10 interactors: APP ARF1 CCDC155 GOLGA8EP GOLGA8F NAPA STX4 STX5 STX6 USO1	15 interactors: EEA1 GOPC GOSR2 MARCH2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX4 STX7 VAMP4 VPS11 VPS18
Entrez ID		9570	10228
HPRD ID		04937	07231
Ensembl ID		ENSG00000108433	ENSG00000135823
Uniprot IDs		I3L4Z6 O14653	B4DR17 O43752
PDB IDs		3EG9	2NPS
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Transport Membrane Fusion Vesicle Fusion Vesicle Organization Establishment Of Localization In Cell Organelle Fusion Cellular Localization Vesicle-mediated Transport Intracellular Transport Membrane Organization Protein Transport Establishment Of Protein Localization Vesicle Docking Post-Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus Membrane Docking Intracellular Protein Transport Protein Localization Cellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Protein Localization Regulation Of Synaptic Transmission Transport Organelle Organization Establishment Of Organelle Localization Regulation Of Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Organelle Localization Golgi Organization Chromosome Localization To Nuclear Envelope Involved In Synapsis ER To Golgi Vesicle-mediated Transport Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Golgi Vesicle Docking SNARE Complex Disassembly Collateral Sprouting In Absence Of Injury Golgi Disassembly Transition Metal Ion Homeostasis Regulation Of Exocytosis Regulation Of Synaptic Plasticity Collateral Sprouting Axon Midline Choice Point Recognition Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Synaptic Vesicle Priming Establishment Of Vesicle Localization Endosomal Transport Vesicle Localization Axon Choice Point Recognition Golgi Ribbon Formation	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Vesicle Organization Establishment Of Localization In Cell Membrane Organization Cellular Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Transport Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Golgi Vesicle Transport Cellular Protein Localization Synaptic Vesicle Transport Intracellular Protein Transport Exocytosis Regulation Of Establishment Of Protein Localization To Plasma Membrane Organelle Organization Organelle Localization Synaptic Vesicle Exocytosis Establishment Of Vesicle Localization Golgi Ribbon Formation Vesicle Localization Secretion By Cell Regulation Of Golgi To Plasma Membrane Protein Transport Synaptic Vesicle Priming SNARE Complex Assembly Secretion Neurotransmitter Secretion Establishment Of Organelle Localization Cellular Protein Complex Assembly Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Endosomal Transport Protein Complex Assembly Vesicle Targeting Synaptic Transmission Intra-Golgi Vesicle-mediated Transport Cellular Macromolecular Complex Assembly Cellular Component Assembly Synaptic Vesicle To Endosome Fusion Cytoplasmic Sequestering Of CFTR Protein
Tagcloud ?		430g bounding came cavus clonic clue creatine deformities discharges electroencephalography epilepsies founder g144w myoclonic myoclonus norway pes photosensitivity predominance ready relentless scoliosis seizures snap spike syndactyly tonic uniformly wheelchair	alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3
Tagcloud (Difference) ?		430g bounding came cavus clonic clue creatine deformities discharges electroencephalography epilepsies founder g144w myoclonic myoclonus norway pes photosensitivity predominance ready relentless scoliosis seizures snap spike syndactyly tonic uniformly wheelchair	alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3
Tagcloud (Intersection) ?