RAB3D and RABIF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RAB3D	RABIF
Description		RAB3D, member RAS oncogene family	RAB interacting factor
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GO Annotations	Cellular Component	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Membrane Secretory Granule Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle	Cytosol Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Exocytosis Protein Transport Regulation Of Exocytosis Bone Resorption Positive Regulation Of Regulated Secretory Pathway	Post-Golgi Vesicle-mediated Transport Small GTPase-mediated Signal Transduction Protein Transport Membrane Fusion
Pathways		Neutrophil degranulation RAB geranylgeranylation
Drugs
Diseases
GWAS		Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)
Interacting Genes		16 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF REP15 RIMS2 RNF32 RPH3AL SYTL4 VRTN	27 interacting genes: EIF3F ITGA2 ITGA3 ITGA5 ITGA6 KIFC3 KYAT3 LAMTOR5 LARP1B LMCD1 LNX1 LRMDA LZTS1 RAB10 RAB15 RAB19 RAB1B RAB3A RAB3C RAB3D RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544
Entrez ID		9545	5877
HPRD ID		05070	04566
Ensembl ID		ENSG00000105514	ENSG00000183155
Uniprot IDs		A0A024R7G2 O95716	P47224 Q53EV1
PDB IDs		2GF9	1FWQ 2FU5
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization Protein Transport Vesicle-mediated Transport Intracellular Protein Localization Cellular Localization Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Intracellular Protein Transport Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Intracellular Transport Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Response To Endoplasmic Reticulum Stress Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Post-Golgi Vesicle-mediated Transport Glycogen Biosynthetic Process Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Vesicle-mediated Transport Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Glycogen Biosynthetic Process Small GTPase Binding Plasma Membrane Organization Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Establishment Of Protein Localization Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Polysaccharide Biosynthetic Process Membrane Organization Regulation Of Generation Of Precursor Metabolites And Energy Molecular Function Activator Activity Establishment Of Localization In Cell Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Transport Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of Excitatory Postsynaptic Potential Secretion By Cell Regulation Of Fatty Acid Oxidation Endosome Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of D-glucose Import Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Lipid Transport Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Glycogen Metabolic Process Positive Regulation Of Protein Localization Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Exocytosis Positive Regulation Of Transport	Myosin V Binding GTPase Activity GTP Binding Integrin Complex Exocytosis GTP-dependent Protein Binding Integrin-mediated Signaling Pathway Cell-matrix Adhesion Cell-substrate Junction Assembly Secretion By Cell Cell-substrate Junction Organization Cell Junction Organization Synaptic Vesicle Positive Regulation Of Regulated Secretory Pathway Perinuclear Region Of Cytoplasm Secretory Vesicle Cell-cell Adhesion Cell-substrate Adhesion Secretion Skin Morphogenesis Cellular Component Maintenance Protein Transport G Protein Activity Intracellular Protein Localization Regulation Of Exocytosis Mesodermal Cell Differentiation Positive Regulation Of Exocytosis Laminin Binding Focal Adhesion Hydrolase Activity Establishment Of Protein Localization Signaling Receptor Activity Golgi Organization Cell Adhesion Mediated By Integrin Nucleotide Binding Response To Muscle Activity Regulation Of Regulated Secretory Pathway Metal Ion Binding Integrin Alpha6-beta4 Complex Regulation Of Vesicle-mediated Transport Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Viral Process Integrin Binding Vesicle-mediated Transport Axonogenesis Cell Adhesion Integrin Alpha6-beta1 Complex Positive Regulation Of Epithelial Cell Migration Integrin Alpha3-beta1 Complex
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