RAB3D and RAB3IP

Number of citations of the paper that reports this interaction (PMID 7532276)
19

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		RAB3D	RAB3IP
Gene Name		RAB3D, member RAS oncogene family	RAB3A interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Endosome Plasma Membrane Synaptic Vesicle Transport Vesicle Secretory Granule Membrane Zymogen Granule Extracellular Vesicular Exosome	Nucleus Centrosome Cytosol Cytoskeleton Lamellipodium Ciliary Basal Body
	Molecular Function	GTPase Activity GTP Binding GDP Binding Myosin V Binding GTPase Binding	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Peptidyl-cysteine Methylation Rab Protein Signal Transduction Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway	Protein Targeting To Membrane Golgi To Plasma Membrane Transport Organelle Organization Positive Regulation Of Rab GTPase Activity Protein Localization To Organelle Cilium Assembly
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		HDL cholesterol ( 23505323)
Protein-Protein Interactions		12 interactors: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RIMS2 RNF32 RPH3AL	19 interactors: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A ZNF410
Entrez ID		9545	117177
HPRD ID		05070	10565
Ensembl ID		ENSG00000105514	ENSG00000127328
Uniprot IDs		O95716	Q96QF0
PDB IDs		2GF9
Enriched GO Terms of Interacting Partners?		Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Establishment Of Protein Localization Intracellular Protein Transport Intracellular Transport Cellular Localization Protein Transport Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Peripheral Nervous System Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Membrane Organization Regulation Of Fatty Acid Beta-oxidation Protein Targeting Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Negative Regulation Of Lipid Transport Glycogen Biosynthetic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Transport Positive Regulation Of Glucose Metabolic Process Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Cellular Polysaccharide Biosynthetic Process Regulation Of Glycogen Metabolic Process Schwann Cell Development Positive Regulation Of Glucose Transport Polysaccharide Biosynthetic Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Translation Vesicle-mediated Transport Schwann Cell Differentiation Negative Regulation Of Transmembrane Transport Regulation Of Glucose Import Transport Regulation Of Lipid Catabolic Process Glycogen Metabolic Process Positive Regulation Of Catalytic Activity Exocytosis Glycogen Cell Differentiation Involved In Embryonic Placenta Development Protein Localization To Membrane Regulation Of Vesicle-mediated Transport Regulation Of Generation Of Precursor Metabolites And Energy Polysaccharide Metabolic Process Regulation Of Fatty Acid Metabolic Process Post-Golgi Vesicle-mediated Transport Regulation Of Glucose Transport Glial Cell Development Regulation Of Lipid Transport	Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Fusion To Target Membrane Protein Secretion Protein Localization Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Ras Protein Signal Transduction Organelle Fusion Protein Transport Establishment Of Protein Localization Establishment Of Organelle Localization Exocytosis Positive Regulation Of Regulated Secretory Pathway Membrane Fusion Organelle Localization Vesicle-mediated Transport Regulation Of Regulated Secretory Pathway Secretion By Cell Vesicle Organization Keratinization Skin Development Regulation Of Cellular Localization Vesicle Fusion Synaptic Transmission Organelle Organization Regulation Of Neuronal Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Small GTPase Mediated Signal Transduction Epidermis Development Secretion Positive Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Secretion N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Positive Regulation Of Transport Cellular Protein Localization Keratinocyte Differentiation Constitutive Secretory Pathway Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane
Tagcloud ?		cease chief he4 imchief immortomice immortomouse imspem lineages mal2 metaplasia metaplasias metaplastic myelin nonpermissive owing oxyntic pepsinogen permissive preneoplastic proliferate reliance resemble secrete sole spasmolytic spem stomach tff2 transdifferentiation	11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses
Tagcloud (Difference) ?		cease chief he4 imchief immortomice immortomouse imspem lineages mal2 metaplasia metaplasias metaplastic myelin nonpermissive owing oxyntic pepsinogen permissive preneoplastic proliferate reliance resemble secrete sole spasmolytic spem stomach tff2 transdifferentiation	11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses
Tagcloud (Intersection) ?