RAB3D and AP1M2

Number of citations of the paper that reports this interaction (PubMedID 21163940)
58

Data Source:
BioGRID (two hybrid)

		RAB3D	AP1M2
Description		RAB3D, member RAS oncogene family	adaptor related protein complex 1 subunit mu 2
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Membrane Secretory Granule Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding	Protein Binding Clathrin Adaptor Activity
	Biological Process	Exocytosis Protein Transport Regulation Of Exocytosis Bone Resorption Positive Regulation Of Regulated Secretory Pathway	Protein Targeting Intracellular Protein Transport Vesicle Targeting Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Establishment Of Localization In Cell Basolateral Protein Secretion
Pathways		Neutrophil degranulation RAB geranylgeranylation	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)	Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 27863252) Plateletcrit ( 27863252 32888494) Red cell distribution width ( 27863252 28957414 32888494)
Interacting Genes		16 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF REP15 RIMS2 RNF32 RPH3AL SYTL4 VRTN	20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		9545	10053
HPRD ID		05070	06296
Ensembl ID		ENSG00000105514	ENSG00000129354
Uniprot IDs		A0A024R7G2 O95716	Q53GI5 Q9Y6Q5
PDB IDs		2GF9
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization Protein Transport Vesicle-mediated Transport Intracellular Protein Localization Cellular Localization Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Intracellular Protein Transport Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Intracellular Transport Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Response To Endoplasmic Reticulum Stress Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Post-Golgi Vesicle-mediated Transport Glycogen Biosynthetic Process Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Vesicle-mediated Transport Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Glycogen Biosynthetic Process Small GTPase Binding Plasma Membrane Organization Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Establishment Of Protein Localization Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Polysaccharide Biosynthetic Process Membrane Organization Regulation Of Generation Of Precursor Metabolites And Energy Molecular Function Activator Activity Establishment Of Localization In Cell Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Transport Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of Excitatory Postsynaptic Potential Secretion By Cell Regulation Of Fatty Acid Oxidation Endosome Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of D-glucose Import Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Lipid Transport Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Glycogen Metabolic Process Positive Regulation Of Protein Localization Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Exocytosis Positive Regulation Of Transport	AP-1 Adaptor Complex Early Endosome Melanosome Assembly Clathrin Adaptor Activity Basolateral Protein Secretion Platelet Dense Granule Organization Clathrin-coated Pit Vesicle-mediated Transport Membrane Coat Melanosome Organization Pigment Granule Organization Trans-Golgi Network Membrane Cytoplasmic Vesicle Clathrin Adaptor Complex Import Into Cell Intracellular Transport Establishment Of Localization In Cell Synaptic Vesicle Endocytosis Secretory Granule Organization Regulation Of Amyloid Fibril Formation GTP-dependent Protein Binding Regulation Of Vesicle-mediated Transport Cellular Localization Lysosomal Membrane Secretion By Cell Presynapse Astrocyte Activation Involved In Immune Response Clathrin Binding Clathrin-coated Vesicle Membrane Golgi Apparatus Protein Localization To Extracellular Region Protein Secretion Establishment Of Protein Localization To Extracellular Region Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Intracellular Protein Localization Endosome Protein Transport Secretion Positive Regulation Of Regulated Secretory Pathway Vesicle Organization Positive Regulation Of Transport Cytoplasmic Vesicle Membrane Receptor-mediated Endocytosis Endosome To Melanosome Transport Establishment Of Protein Localization Golgi To Lysosome Transport Clathrin-coated Endocytic Vesicle Membrane Clathrin-coated Vesicle
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