CIR1 and CEP76

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CIR1	CEP76
Gene Name		corepressor interacting with RBPJ, 1	centrosomal protein 76kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Cytoplasm Microtubule Organizing Center Nuclear Speck	Centrosome Centriole Cytosol Protein Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding	Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter MRNA Processing RNA Splicing Negative Regulation Of Transcription, DNA-templated	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Regulation Of Centriole Replication
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CEP76 HDAC2 NCOR2 NEK6 RBPJ RP9 SAP30 SNW1 SRSF2 TCEA1 U2AF1	48 interactors: AKAP7 BANP BZRAP1 C22orf39 CABP5 CCDC92 CCNK CIR1 COIL CRYBA4 CSNK1G1 CUTC DCTD DZIP1L EAF1 EP400NL FAM90A1 GDAP2 GFAP HSPB7 ILVBL KIAA1143 KIAA1279 KLHDC4 LATS1 MAGEA11 MBD3 NHLRC2 PAICS PARD6B PIN1 PLCB1 POM121 RADIL RNF128 RPL9 SALL2 SH2D4A TBC1D27 TOB2 TSSC4 TTC21A TUFT1 TXNDC9 WDFY3 ZBTB24 ZMAT2 ZNF85
Entrez ID		9541	79959
HPRD ID		05568	12694
Ensembl ID		ENSG00000138433	ENSG00000101624
Uniprot IDs		Q86X95	B4DP81 Q8TAP6
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Splicing Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Notch Signaling Pathway Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated RNA Processing Regulation Of Cardiac Muscle Cell Proliferation DNA-templated Transcription, Initiation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Negative Regulation Of Gene Expression Positive Regulation Of Viral Transcription Regulation Of Heart Growth Biosynthetic Process Regulation Of Cardiac Muscle Tissue Development Lung Epithelial Cell Differentiation Striated Muscle Tissue Development Lung Cell Differentiation Muscle Tissue Development Lung Epithelium Development MRNA Export From Nucleus Regulation Of Viral Transcription Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Epidermal Cell Fate Specification Positive Regulation Of Viral Process DNA-templated Transcription, Termination RNA Export From Nucleus Negative Regulation Of Gene Expression, Epigenetic Regulation Of Organelle Organization
Tagcloud ?		arabidopsis biotrophic branch characterise constitutive dc3000 defence deficient4 displays eds1 epistasis greatest grown lies luc modulated pad4 pathogen phytoalexin plants pseudomonas pst sa salicylic stunted susceptibility1 syringae temperatures tomato	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 rpgrip1 rpgrip1l tgl throw ttl
Tagcloud (Difference) ?		arabidopsis biotrophic branch characterise constitutive dc3000 defence deficient4 displays eds1 epistasis greatest grown lies luc modulated pad4 pathogen phytoalexin plants pseudomonas pst sa salicylic stunted susceptibility1 syringae temperatures tomato	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 rpgrip1 rpgrip1l tgl throw ttl
Tagcloud (Intersection) ?