CIR1 and TCEA1

Number of citations of the paper that reports this interaction (PMID 11591653)
37

Data Source:
HPRD (in vivo)

		CIR1	TCEA1
Gene Name		corepressor interacting with RBPJ, 1	transcription elongation factor A (SII), 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Cytoplasm Microtubule Organizing Center Nuclear Speck	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter MRNA Processing RNA Splicing Negative Regulation Of Transcription, DNA-templated	DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Erythrocyte Differentiation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways			Nucleotide Excision Repair Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CEP76 HDAC2 NCOR2 NEK6 RBPJ RP9 SAP30 SNW1 SRSF2 TCEA1 U2AF1	17 interactors: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61
Entrez ID		9541	6917
HPRD ID		05568	03252
Ensembl ID		ENSG00000138433	ENSG00000187735
Uniprot IDs		Q86X95	B7Z4S1 P23193
PDB IDs			1TFI 3NDQ
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Splicing Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Notch Signaling Pathway Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated RNA Processing Regulation Of Cardiac Muscle Cell Proliferation DNA-templated Transcription, Initiation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Negative Regulation Of Gene Expression Positive Regulation Of Viral Transcription Regulation Of Heart Growth Biosynthetic Process Regulation Of Cardiac Muscle Tissue Development Lung Epithelial Cell Differentiation Striated Muscle Tissue Development Lung Cell Differentiation Muscle Tissue Development Lung Epithelium Development MRNA Export From Nucleus Regulation Of Viral Transcription Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Epidermal Cell Fate Specification Positive Regulation Of Viral Process DNA-templated Transcription, Termination RNA Export From Nucleus Negative Regulation Of Gene Expression, Epigenetic Regulation Of Organelle Organization	Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated MRNA Processing Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Histone H2B Ubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Cell Fate Commitment Involved In Formation Of Primary Germ Layer Positive Regulation Of Gene Expression MRNA Metabolic Process Gene Expression Positive Regulation Of Cellular Biosynthetic Process Endodermal Cell Differentiation RNA Processing Regulation Of Nitrogen Compound Metabolic Process Endoderm Formation Transcription Elongation From RNA Polymerase II Promoter Stem Cell Maintenance Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Myeloid Cell Differentiation Endoderm Development MRNA Polyadenylation Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Histone Ubiquitination RNA Polyadenylation Negative Regulation Of Cell Differentiation Stem Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Protein Monoubiquitination Regulation Of Histone Modification Wnt Signaling Pathway Formation Of Primary Germ Layer Positive Regulation Of Viral Transcription
Tagcloud ?		arabidopsis biotrophic branch characterise constitutive dc3000 defence deficient4 displays eds1 epistasis greatest grown lies luc modulated pad4 pathogen phytoalexin plants pseudomonas pst sa salicylic stunted susceptibility1 syringae temperatures tomato	arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5
Tagcloud (Difference) ?		arabidopsis biotrophic branch characterise constitutive dc3000 defence deficient4 displays eds1 epistasis greatest grown lies luc modulated pad4 pathogen phytoalexin plants pseudomonas pst sa salicylic stunted susceptibility1 syringae temperatures tomato	arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5
Tagcloud (Intersection) ?