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RASAL2 and USHBP1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
RASAL2
USHBP1
Gene Name
RAS protein activator like 2
Usher syndrome 1C binding protein 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane
Molecular Function
Ras GTPase Activator Activity
Protein Binding
Protein Binding
PDZ Domain Binding
Biological Process
Signal Transduction
Positive Regulation Of Ras GTPase Activity
Negative Regulation Of Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS
Body mass index (
19079260
)
Immune response to smallpox vaccine (IL-6) (
22542470
)
Obesity-related traits (
23251661
)
Weight (
19079260
)
Protein-Protein Interactions
6 interactors:
CTAGE5
NFKBIB
TRAF1
UBC
USHBP1
YWHAG
124 interactors:
ABLIM1
AKAP9
ANKRD36BP1
ARFIP2
ARNT2
ATP5O
BCL10
BET1
C10orf10
C1orf109
C1orf216
C6orf165
CCDC116
CCDC120
CCDC121
CCDC146
CCDC148
CCDC22
CCDC24
CCDC33
CCDC87
CCHCR1
CCNK
CENPP
CEP63
CEP68
CHCHD3
CNNM3
COPS4
COPS8
CTNNBIP1
CTTNBP2NL
DTNB
DYDC1
EIF4E2
ERCC1
EXOC7
EXOC8
FAM107A
FAM110A
FAM124B
FANCG
FATE1
FBF1
FTL
GATAD2B
GCC1
GFI1B
GIT2
GMCL1P1
GNG4
GOLGA8EP
GOLGA8F
GPSM1
GPSM3
GTF2H1
HAUS1
HGS
IFT20
IL16
IMP3
ING3
INPP1
INTS4
KANSL1
KIAA0753
KLC3
KLC4
KLHL38
KLHL42
KPNA2
KRT15
KRT19
KRT20
KRT31
KRT38
KRT40
KRT79
LENG1
LINC00526
MAGEB4
MCM7
MCRS1
MED28
MED4
MOS
MRPS23
NCAPH2
NDC80
NDE1
NGFRAP1
NOC4L
PARVG
PMF1
PPP1R7
PPP2R5D
PRC1
PRKAA2
RASAL2
RECK
RIBC2
RNF20
SEC14L4
SERTAD3
SH2D4A
SMARCD1
SMARCE1
STX11
SYNJ2BP
THADA
THOC1
TRIM54
TSG101
TUBGCP4
TXLNA
TXLNB
UBE2W
UBXN11
USH1C
VPS28
ZFYVE26
ZNF483
ZNF765
ZNRF2P1
Entrez ID
9462
83878
HPRD ID
05845
18276
Ensembl ID
ENSG00000075391
ENSG00000130307
Uniprot IDs
A8K2P3
Q9UJF2
G8JLM4
Q8N6Y0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Type I Interferon Production
Toll-like Receptor 4 Signaling Pathway
Regulation Of Type I Interferon Production
Toll-like Receptor Signaling Pathway
G2/M Transition Of Mitotic Cell Cycle
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Regulation Of Innate Immune Response
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Transferase Activity
Apoptotic Signaling Pathway
Regulation Of Apoptotic Process
Positive Regulation Of Cytokine Production
Viral Protein Processing
Regulation Of Cell Death
Regulation Of Metabolic Process
Immune Response-regulating Signaling Pathway
Cellular Response To Organic Substance
Notch Receptor Processing
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Virion Assembly
Regulation Of Cytokine Production
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Glycogen Biosynthetic Process
Intracellular Transport Of Virus
Positive Regulation Of Apoptotic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Organelle Organization
Cell Cycle Process
Cell Cycle
Cell Division
Mitotic Cell Cycle
Chromosome Organization
Mitotic Cell Cycle Process
Establishment Of Localization In Cell
Cytoskeleton Organization
Cellular Localization
Microtubule-based Process
Microtubule Cytoskeleton Organization
Chromatin Organization
Chromatin Modification
G2/M Transition Of Mitotic Cell Cycle
Spindle Organization
Regulation Of Metabolic Process
Intracellular Transport Of Virus
Intracellular Transport
Mitotic Nuclear Division
Centrosome Organization
Cellular Process
Cullin Deneddylation
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Establishment Of Spindle Orientation
Microtubule Organizing Center Organization
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Protein Deneddylation
Viral Protein Processing
Establishment Of Cell Polarity
Histone H4 Acetylation
Spindle Localization
Cellular Response To DNA Damage Stimulus
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Membrane Organization
Histone H4-K16 Acetylation
Nucleosome Disassembly
ATP-dependent Chromatin Remodeling
Nucleotide-excision Repair, DNA Damage Removal
Microtubule Nucleation
Organelle Fusion
Protein Targeting To Vacuole
Virion Assembly
Tagcloud
?
acted
antagonizing
arhgap24
catalytic
contributes
drives
encodes
gap
gtpase
independently
invasion
luminal
mesenchymal
metastasis
microrna
module
oncogenic
opposed
overexpressed
poorly
promoted
promotes
rac1
relapse
subset
tnbc
triple
tumorigenesis
Tagcloud (Difference)
?
acted
antagonizing
arhgap24
catalytic
contributes
drives
encodes
gap
gtpase
independently
invasion
luminal
mesenchymal
metastasis
microrna
module
oncogenic
opposed
overexpressed
poorly
promoted
promotes
rac1
relapse
subset
tnbc
triple
tumorigenesis
Tagcloud (Intersection)
?