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RASAL2 and NFKBIB
Number of citations of the paper that reports this interaction (PubMedID
14743216
)
0
Data Source:
HPRD
(in vitro)
RASAL2
NFKBIB
Description
RAS protein activator like 2
NFKB inhibitor beta
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Nucleus
Cytoplasm
Cytosol
Molecular Function
GTPase Activator Activity
Protein Binding
Transcription Coactivator Activity
Protein Binding
Biological Process
Response To Dietary Excess
Signal Transduction
Response To Glucose
Gene Expression
Multicellular Organism Growth
Adipose Tissue Development
Regulation Of Intracellular Signal Transduction
Regulation Of Protein Activation Cascade
DNA-templated Transcription
Inflammatory Response
Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of DNA-templated Transcription
Cellular Response To Lipopolysaccharide
Pathways
Regulation of RAS by GAPs
RND3 GTPase cycle
RND1 GTPase cycle
Activation of NF-kappaB in B cells
RIP-mediated NFkB activation via ZBP1
TAK1-dependent IKK and NF-kappa-B activation
TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS
Bipolar disorder (
28115744
)
Body mass index (
19079260
26426971
)
Body mass index (age <50) (
26426971
)
Body mass index x sex x age interaction (4df test) (
26426971
)
Immune response to smallpox vaccine (IL-6) (
22542470
)
Obesity-related traits (
23251661
)
Plateletcrit (
32888494
)
Weight (
19079260
)
Liver enzyme levels (gamma-glutamyl transferase) (
33972514
)
Interacting Genes
10 interacting genes:
HMGB1
MCC
MEOX2
MIA2
NFKBIB
SYNJ1
TRAF1
UBC
USHBP1
YWHAG
43 interacting genes:
APP
BAK1
BTBD6
BTRC
CDC25A
CHUK
CSNK2A1
CUL1
DNAJA3
ESR2
FHL3
GIT2
IKBKB
IKBKG
KPNA2
LRPPRC
MCC
MTIF2
NCOR2
NDUFB7
NFKB1
NFKB2
NFKBIA
NGFR
NKIRAS1
NKIRAS2
PDCD2
POLR1A
POLR1B
POLR1C
POLR1D
POLR1E
POLR1G
POLR2H
POLR2L
PPARG
RASAL2
REL
RELA
RXRA
SKP1
TSPAN1
VPS52
Entrez ID
9462
4793
HPRD ID
05845
07260
Ensembl ID
ENSG00000075391
ENSG00000104825
Uniprot IDs
A0A8Q3SIU1
A0A8Q3SJF6
A8K2P3
Q9UJF2
G5E9C2
Q15653
PDB IDs
9CK0
Enriched GO Terms of Interacting Partners
?
Regulation Of T Cell Mediated Immune Response To Tumor Cell
Regulation Of Response To Tumor Cell
RNA Polymerase I Complex
Non-canonical NF-kappaB Signal Transduction
DNA-directed RNA Polymerase Complex
Canonical NF-kappaB Signal Transduction
Nucleoplasm
DNA-directed RNA Polymerase Activity
Intracellular Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Transcription By RNA Polymerase I
DNA-templated Transcription
Intracellular Signaling Cassette
Negative Regulation Of Canonical NF-kappaB Signal Transduction
I-kappaB/NF-kappaB Complex
Cytosol
Regulation Of Intracellular Signal Transduction
RNA Polymerase III Complex
Regulation Of MiRNA Metabolic Process
Negative Regulation Of Signal Transduction
Nucleobase-containing Compound Biosynthetic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
RRNA Transcription
Tumor Necrosis Factor-mediated Signaling Pathway
IkappaB Kinase Complex
Negative Regulation Of MiRNA Transcription
Regulation Of Signal Transduction
Nucleus
DNA Binding
Macromolecule Biosynthetic Process
Regulation Of MiRNA Transcription
Transferrin Receptor Binding
Signal Transduction Involved In Regulation Of Gene Expression
Immune Response-activating Cell Surface Receptor Signaling Pathway
RNA Metabolic Process
Cellular Response To Tumor Necrosis Factor
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of DNA-binding Transcription Factor Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
NF-kappaB P50/p65 Complex
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Response To Cytokine
Response To Peptide
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Response To Tumor Necrosis Factor
Positive Regulation Of T Cell Receptor Signaling Pathway
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Tagcloud (Difference)
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Tagcloud (Intersection)
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