RASAL2 and MIA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RASAL2	MIA2
Description		RAS protein activator like 2	MIA SH3 domain ER export factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	GTPase Activator Activity Protein Binding	Protein Binding Enzyme Activator Activity Cargo Receptor Activity
	Biological Process	Response To Dietary Excess Signal Transduction Response To Glucose Gene Expression Multicellular Organism Growth Adipose Tissue Development Regulation Of Intracellular Signal Transduction Regulation Of Protein Activation Cascade	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Secretion Protein Exit From Endoplasmic Reticulum Vesicle Cargo Loading Lipoprotein Transport Protein Localization To Endoplasmic Reticulum Exit Site
Pathways		Regulation of RAS by GAPs RND3 GTPase cycle RND1 GTPase cycle	Cargo concentration in the ER
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Body mass index ( 19079260 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Immune response to smallpox vaccine (IL-6) ( 22542470) Obesity-related traits ( 23251661) Plateletcrit ( 32888494) Weight ( 19079260)
Interacting Genes		10 interacting genes: HMGB1 MCC MEOX2 MIA2 NFKBIB SYNJ1 TRAF1 UBC USHBP1 YWHAG	15 interacting genes: CCHCR1 CEP57 DGCR6 EMILIN1 GRB2 MAGEB18 PDCD6 PSMA3 RASAL2 RSPH1 SEC23A SEC24C SS18L1 TLE5 TTC23L
Entrez ID		9462	4253
HPRD ID		05845	03680
Ensembl ID		ENSG00000075391	ENSG00000150527
Uniprot IDs		A0A8Q3SIU1 A0A8Q3SJF6 A8K2P3 Q9UJF2	Q4G155 Q59FD2 Q96PC5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Response To Tumor Cell	COPII Vesicle Coat Endoplasmic Reticulum Exit Site ER To Golgi Transport Vesicle Membrane Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway COPII-coated Vesicle Cargo Loading Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Cargo Loading Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Developmental Process
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