SIGLEC6 and ZNF655

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SIGLEC6	ZNF655
Description		sialic acid binding Ig like lectin 6	zinc finger protein 655
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Membrane	Nucleus Nucleolus Cytoplasm
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Cell Adhesion Cell-cell Signaling	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Generic Transcription Pathway
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Carotid intima media thickness ( 26343869)	Serum metabolite levels ( 23093944)
Interacting Genes		7 interacting genes: FHL2 LEP LGALS3BP MALL PAX6 TCF4 ZNF655	156 interacting genes: ACSL6 ANKRD11 AP1M1 ASB6 ASMTL ATOSB ATPAF2 BARD1 BORCS6 BYSL C8orf34 C8orf74 CAPN7 CARD9 CBY2 CCDC116 CCDC179 CCDC57 CCDC74A CCHCR1 CCNH CDC37 CDK4 CDR2L CEP57L1 CPNE7 CRACR2A CWF19L2 DBF4B DEUP1 DPF2 DUSP4 EGLN3 EIF4EBP1 EMILIN1 EVL EXOSC5 FADS2 FAM81A FAM81B FAM90A1 FARS2 FBXL9P FHL2 FKBP6 GEM GFAP GSTP1 GUCD1 HAPLN2 HEXIM2 HOMER3 HOOK1 HOXB5 HPCAL1 HSD3B7 HTT HUNK IDI1 IMP3 INTS10 INTS13 IP6K3 ITGB5 JRK KIFC3 KRT40 KRT76 KRT85 KRT86 KRTAP4-12 KRTAP5-9 KRTAP9-8 LCE3C LCE4A LCE5A LGALS14 LMO2 LNX1 MACO1 MAD2L2 MAGEA11 MAGEA2B MBD3 MED21 MEMO1 METTL21A MIS18A MITD1 MPP3 MRFAP1 MRPL28 MTMR9 MTUS2 MXI1 NAA10 NDC80 NECAB2 NGB NOTUM NUDT21 NUDT22 NXT2 OIP5 OSTF1 OTUD4 P2RX7 PBX3 PCSK5 PFKFB1 POLR1C PRR35 RIN3 RINT1 RRM1 RUNX1T1 SH2D4A SIGLEC6 SLC12A4 SMARCD1 SMG9 SPANXN2 SPRED1 SPRY3 SRGAP2B SZT2 TCEANC TEKT4 TEX28 THAP6 TIMM10 TLK1 TNS2 TRAF2 TRAF5 TRAPPC2 TRAPPC2B TRIM37 TRIM41 TRIM72 TRIP13 TSPYL4 TXNDC9 USHBP1 VAV1 VPS26C VPS9D1 XPA YPEL5 ZBTB16 ZC2HC1C ZNF330 ZNF552 ZNF648 ZNF792 ZNF837
Entrez ID		946	79027
HPRD ID		16058	11673
Ensembl ID		ENSG00000105492	ENSG00000197343
Uniprot IDs		O43699	Q8N720
PDB IDs			8PK6
Enriched GO Terms of Interacting Partners?		Atrial Cardiac Muscle Cell Development Regulation Of Transcription By RNA Polymerase II Elastin Metabolic Process Carbohydrate Homeostasis Leptin Receptor Binding Activation Of Protein Kinase C Activity Regulation Of Lipoprotein Lipid Oxidation Glucose Homeostasis Positive Regulation Of Fat Cell Apoptotic Process Positive Regulation Of Luteinizing Hormone Secretion Blood Vessel Development Regulation Of Follicle-stimulating Hormone Secretion Bone Mineralization Involved In Bone Maturation Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Follicle-stimulating Hormone Secretion Cellular Response To L-ascorbic Acid Positive Regulation Of Hepatic Stellate Cell Activation Response To Vitamin E Prostaglandin Secretion Response To L-ascorbic Acid Regulation Of Fat Cell Apoptotic Process Regulation Of Glucagon Secretion Regulation Of Intestinal Cholesterol Absorption Neuron Development Glycerol Biosynthetic Process Negative Regulation Of Glucagon Secretion Negative Regulation Of Glutamine Transport Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Habenula Development Oligodendrocyte Cell Fate Specification Pallium Development Formation Of Anatomical Boundary Glial Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Regulation Of Neuron Differentiation Cerebral Cortex Regionalization Lacrimal Gland Development Telencephalon Regionalization TFIIB-class Transcription Factor Binding Beta-catenin-TCF7L2 Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Anatomical Structure Formation Involved In Morphogenesis Forebrain Neuron Fate Commitment Ventral Spinal Cord Development Iris Morphogenesis	Protein Binding Identical Protein Binding Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition TRAF2-GSTP1 Complex Keratinization Intermediate Filament
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