ZNF655 and NOTUM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF655	NOTUM
Description		zinc finger protein 655	notum, palmitoleoyl-protein carboxylesterase
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Extracellular Region Endoplasmic Reticulum Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Phospholipase C Activity Protein Binding Lipase Activity Hydrolase Activity Carboxylic Ester Hydrolase Activity Protein-containing Complex Destabilizing Activity Palmitoleyl Hydrolase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Bone Mineralization Bone Development Negative Regulation Of Canonical Wnt Signaling Pathway Protein Depalmitoleylation
Pathways		Generic Transcription Pathway	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Release of Hh-Np from the secreting cell Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Serum metabolite levels ( 23093944)	Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) Diverticular disease ( 30177863)
Interacting Genes		156 interacting genes: ACSL6 ANKRD11 AP1M1 ASB6 ASMTL ATOSB ATPAF2 BARD1 BORCS6 BYSL C8orf34 C8orf74 CAPN7 CARD9 CBY2 CCDC116 CCDC179 CCDC57 CCDC74A CCHCR1 CCNH CDC37 CDK4 CDR2L CEP57L1 CPNE7 CRACR2A CWF19L2 DBF4B DEUP1 DPF2 DUSP4 EGLN3 EIF4EBP1 EMILIN1 EVL EXOSC5 FADS2 FAM81A FAM81B FAM90A1 FARS2 FBXL9P FHL2 FKBP6 GEM GFAP GSTP1 GUCD1 HAPLN2 HEXIM2 HOMER3 HOOK1 HOXB5 HPCAL1 HSD3B7 HTT HUNK IDI1 IMP3 INTS10 INTS13 IP6K3 ITGB5 JRK KIFC3 KRT40 KRT76 KRT85 KRT86 KRTAP4-12 KRTAP5-9 KRTAP9-8 LCE3C LCE4A LCE5A LGALS14 LMO2 LNX1 MACO1 MAD2L2 MAGEA11 MAGEA2B MBD3 MED21 MEMO1 METTL21A MIS18A MITD1 MPP3 MRFAP1 MRPL28 MTMR9 MTUS2 MXI1 NAA10 NDC80 NECAB2 NGB NOTUM NUDT21 NUDT22 NXT2 OIP5 OSTF1 OTUD4 P2RX7 PBX3 PCSK5 PFKFB1 POLR1C PRR35 RIN3 RINT1 RRM1 RUNX1T1 SH2D4A SIGLEC6 SLC12A4 SMARCD1 SMG9 SPANXN2 SPRED1 SPRY3 SRGAP2B SZT2 TCEANC TEKT4 TEX28 THAP6 TIMM10 TLK1 TNS2 TRAF2 TRAF5 TRAPPC2 TRAPPC2B TRIM37 TRIM41 TRIM72 TRIP13 TSPYL4 TXNDC9 USHBP1 VAV1 VPS26C VPS9D1 XPA YPEL5 ZBTB16 ZC2HC1C ZNF330 ZNF552 ZNF648 ZNF792 ZNF837	1 interacting genes: ZNF655
Entrez ID		79027	147111
HPRD ID		11673	14073
Ensembl ID		ENSG00000197343	ENSG00000185269
Uniprot IDs		Q8N720	Q6P988
PDB IDs		8PK6	4UYU 4UYW 4UYZ 4UZ1 4UZ5 4UZ6 4UZ7 4UZ9 4UZA 4UZL 4UZQ 4WBH 6R8P 6R8Q 6R8R 6T2H 6T2K 6TR5 6TR6 6TR7 6TUZ 6TV4 6YSK 6YUW 6YUY 6YV0 6YV2 6YV4 6YXI 6ZUV 6ZVL 6ZYF 7ARG 7B2V 7B2Y 7B2Z 7B37 7B3F 7B3G 7B3H 7B3I 7B3P 7B3X 7B45 7B4X 7B50 7B7W 7B7X 7B7Y 7B84 7B86 7B87 7B89 7B8A 7B8C 7B8D 7B8F 7B8G 7B8J 7B8K 7B8L 7B8M 7B8N 7B8O 7B8U 7B8X 7B8Y 7B8Z 7B98 7B99 7B9D 7B9I 7B9N 7B9U 7BA1 7BAC 7BAP 7BC8 7BC9 7BCC 7BCD 7BCF 7BCH 7BCI 7BCK 7BCL 7BD2 7BD3 7BD4 7BD5 7BD6 7BD8 7BD9 7BDA 7BDB 7BDC 7BDD 7BDF 7BDG 7BDH 7BLI 7BLS 7BLT 7BLU 7BLW 7BM1 7BM3 7BM7 7BMB 7BMD 7BN5 7BN8 7BNB 7BNC 7BND 7BNE 7BNF 7BNJ 7BNL 7BO1 7BO2 7BO5 7PJR 7PK3 7PKV 7QVZ 8BSP 8BSQ 8BSR 8BSZ 8BT0 8BT2 8BT5 8BT7 8BT8 8BTA 8BTC 8BTE 8BTH 8BTI
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition TRAF2-GSTP1 Complex Keratinization Intermediate Filament
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