SIGLEC6

Description		sialic acid binding Ig like lectin 6
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Cell Adhesion Cell-cell Signaling
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Carotid intima media thickness ( 26343869)
Interacting Genes		7 interacting genes: FHL2 LEP LGALS3BP MALL PAX6 TCF4 ZNF655
Entrez ID		946
HPRD ID		16058
Ensembl ID		ENSG00000105492
Uniprot IDs		O43699
PDB IDs
Enriched GO Terms of Interacting Partners?		Atrial Cardiac Muscle Cell Development Regulation Of Transcription By RNA Polymerase II Elastin Metabolic Process Carbohydrate Homeostasis Leptin Receptor Binding Activation Of Protein Kinase C Activity Regulation Of Lipoprotein Lipid Oxidation Glucose Homeostasis Positive Regulation Of Fat Cell Apoptotic Process Positive Regulation Of Luteinizing Hormone Secretion Blood Vessel Development Regulation Of Follicle-stimulating Hormone Secretion Bone Mineralization Involved In Bone Maturation Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Follicle-stimulating Hormone Secretion Cellular Response To L-ascorbic Acid Positive Regulation Of Hepatic Stellate Cell Activation Response To Vitamin E Prostaglandin Secretion Response To L-ascorbic Acid Regulation Of Fat Cell Apoptotic Process Regulation Of Glucagon Secretion Regulation Of Intestinal Cholesterol Absorption Neuron Development Glycerol Biosynthetic Process Negative Regulation Of Glucagon Secretion Negative Regulation Of Glutamine Transport Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Habenula Development Oligodendrocyte Cell Fate Specification Pallium Development Formation Of Anatomical Boundary Glial Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Regulation Of Neuron Differentiation Cerebral Cortex Regionalization Lacrimal Gland Development Telencephalon Regionalization TFIIB-class Transcription Factor Binding Beta-catenin-TCF7L2 Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Anatomical Structure Formation Involved In Morphogenesis Forebrain Neuron Fate Commitment Ventral Spinal Cord Development Iris Morphogenesis
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