SIGLEC6 and LGALS3BP

Number of citations of the paper that reports this interaction (PubMedID 25320078)
66

Data Source:
BioGRID (pull down)

		SIGLEC6	LGALS3BP
Description		sialic acid binding Ig like lectin 6	galectin 3 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Membrane	Extracellular Region Extracellular Space Membrane Extracellular Matrix Platelet Dense Granule Lumen Extracellular Exosome Blood Microparticle
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Cell Adhesion Cell-cell Signaling	Cellular Defense Response Cell Adhesion Signal Transduction Vesicle-mediated Transport
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Platelet degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Carotid intima media thickness ( 26343869)	Blood protein levels ( 30072576)
Interacting Genes		7 interacting genes: FHL2 LEP LGALS3BP MALL PAX6 TCF4 ZNF655	24 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 GALNT6 HSP90AA1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1
Entrez ID		946	3959
HPRD ID		16058	02796
Ensembl ID		ENSG00000105492	ENSG00000108679
Uniprot IDs		O43699	Q08380
PDB IDs			1BY2 6GFB
Enriched GO Terms of Interacting Partners?		Atrial Cardiac Muscle Cell Development Regulation Of Transcription By RNA Polymerase II Elastin Metabolic Process Carbohydrate Homeostasis Leptin Receptor Binding Activation Of Protein Kinase C Activity Regulation Of Lipoprotein Lipid Oxidation Glucose Homeostasis Positive Regulation Of Fat Cell Apoptotic Process Positive Regulation Of Luteinizing Hormone Secretion Blood Vessel Development Regulation Of Follicle-stimulating Hormone Secretion Bone Mineralization Involved In Bone Maturation Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Follicle-stimulating Hormone Secretion Cellular Response To L-ascorbic Acid Positive Regulation Of Hepatic Stellate Cell Activation Response To Vitamin E Prostaglandin Secretion Response To L-ascorbic Acid Regulation Of Fat Cell Apoptotic Process Regulation Of Glucagon Secretion Regulation Of Intestinal Cholesterol Absorption Neuron Development Glycerol Biosynthetic Process Negative Regulation Of Glucagon Secretion Negative Regulation Of Glutamine Transport Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Habenula Development Oligodendrocyte Cell Fate Specification Pallium Development Formation Of Anatomical Boundary Glial Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Regulation Of Neuron Differentiation Cerebral Cortex Regionalization Lacrimal Gland Development Telencephalon Regionalization TFIIB-class Transcription Factor Binding Beta-catenin-TCF7L2 Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Anatomical Structure Formation Involved In Morphogenesis Forebrain Neuron Fate Commitment Ventral Spinal Cord Development Iris Morphogenesis	Cell Adhesion Sialic Acid Binding Carbohydrate Binding Wound Healing, Spreading Of Epidermal Cells Cell-matrix Adhesion Laminin Binding Integrin Complex Cell-substrate Adhesion Wound Healing, Spreading Of Cells Response To Muscle Activity Endodermal Cell Differentiation Integrin-mediated Signaling Pathway Proteoglycan Binding Regulation Of Cellular Component Organization Plasma Membrane Extracellular Matrix Cell Surface Cell Migration Integrin Binding Integrin Alpha6-beta1 Complex Integrin Alpha5-beta1 Complex Integrin Alphav-beta1 Complex Response To Activity Positive Regulation Of Cell Adhesion Cell Motility Basement Membrane Positive Regulation Of Cell Migration Regulation Of Locomotion Cell Adhesion Mediated By Integrin Regulation Of Cell Adhesion Secretory Granule Membrane Positive Regulation Of Cell Motility Calcium-independent Cell-matrix Adhesion Positive Regulation Of Locomotion Basement Membrane Organization Negative Regulation Of Apoptotic Signaling Pathway Heterotypic Cell-cell Adhesion Neuregulin Binding C-X3-C Chemokine Binding Cell-substrate Junction Assembly Cell-substrate Junction Organization Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Dendritic Cell Differentiation Signaling Receptor Activity Regulation Of Cell Migration Cell-cell Adhesion Mediated By Integrin Extracellular Exosome Endoplasmic Reticulum Lumen Extracellular Region Regulation Of Cell Motility
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