ZNF655 and GFAP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF655	GFAP
Description		zinc finger protein 655	glial fibrillary acidic protein
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Cytoplasm Lysosome Cytosol Cytoskeleton Intermediate Filament Membrane Cell Projection Cell Body Intermediate Filament Cytoskeleton Glial Cell Projection Astrocyte Projection Astrocyte End-foot Cytoplasmic Side Of Lysosomal Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding Kinase Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Intracellular Protein Transport Gene Expression Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Neuron Projection Development Astrocyte Development Schwann Cell Proliferation Extracellular Matrix Organization Neuron Projection Regeneration Neuron Projection Development Regulation Of Protein-containing Complex Assembly Intermediate Filament-based Process Intermediate Filament Organization Regulation Of Neurotransmitter Uptake Bergmann Glial Cell Differentiation Positive Regulation Of Glial Cell Proliferation Long-term Synaptic Potentiation D-aspartate Import Across Plasma Membrane Regulation Of Chaperone-mediated Autophagy
Pathways		Generic Transcription Pathway	Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases			Alexander disease
GWAS		Serum metabolite levels ( 23093944)	Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)
Interacting Genes		156 interacting genes: ACSL6 ANKRD11 AP1M1 ASB6 ASMTL ATOSB ATPAF2 BARD1 BORCS6 BYSL C8orf34 C8orf74 CAPN7 CARD9 CBY2 CCDC116 CCDC179 CCDC57 CCDC74A CCHCR1 CCNH CDC37 CDK4 CDR2L CEP57L1 CPNE7 CRACR2A CWF19L2 DBF4B DEUP1 DPF2 DUSP4 EGLN3 EIF4EBP1 EMILIN1 EVL EXOSC5 FADS2 FAM81A FAM81B FAM90A1 FARS2 FBXL9P FHL2 FKBP6 GEM GFAP GSTP1 GUCD1 HAPLN2 HEXIM2 HOMER3 HOOK1 HOXB5 HPCAL1 HSD3B7 HTT HUNK IDI1 IMP3 INTS10 INTS13 IP6K3 ITGB5 JRK KIFC3 KRT40 KRT76 KRT85 KRT86 KRTAP4-12 KRTAP5-9 KRTAP9-8 LCE3C LCE4A LCE5A LGALS14 LMO2 LNX1 MACO1 MAD2L2 MAGEA11 MAGEA2B MBD3 MED21 MEMO1 METTL21A MIS18A MITD1 MPP3 MRFAP1 MRPL28 MTMR9 MTUS2 MXI1 NAA10 NDC80 NECAB2 NGB NOTUM NUDT21 NUDT22 NXT2 OIP5 OSTF1 OTUD4 P2RX7 PBX3 PCSK5 PFKFB1 POLR1C PRR35 RIN3 RINT1 RRM1 RUNX1T1 SH2D4A SIGLEC6 SLC12A4 SMARCD1 SMG9 SPANXN2 SPRED1 SPRY3 SRGAP2B SZT2 TCEANC TEKT4 TEX28 THAP6 TIMM10 TLK1 TNS2 TRAF2 TRAF5 TRAPPC2 TRAPPC2B TRIM37 TRIM41 TRIM72 TRIP13 TSPYL4 TXNDC9 USHBP1 VAV1 VPS26C VPS9D1 XPA YPEL5 ZBTB16 ZC2HC1C ZNF330 ZNF552 ZNF648 ZNF792 ZNF837	86 interacting genes: ABI2 AKT1 APP AURKB BIRC2 CAMK2A CARD10 CCDC57 CDC37 CDK1 CEP76 CFAP206 CRYAB CT55 CWF19L2 DSCAM ENKD1 EPM2AIP1 FAM50B FXR1 FXR2 GOLGA2 GRAP2 HGS HOMEZ IKBKG ITSN1 KIAA0408 KRT13 KRT15 KRT19 KRT27 KRT31 KRT39 LENG1 LGALS14 LMO2 MAPK9 MEN1 MOS MYBPHL MYO15B NEFL NEIL3 NEK6 NFKBID NTAQ1 NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PPP1R16B PPP1R18 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCA2 SMARCB1 SRC STAT1 TBC1D21 TBC1D22B TFIP11 TLE5 TP53BP2 TRIM27 TSC1 TUBGCP4 UBASH3A UBE3A VIM YES1 ZC2HC1C ZNF655 ZNF774
Entrez ID		79027	2670
HPRD ID		11673	00675
Ensembl ID		ENSG00000197343	ENSG00000131095
Uniprot IDs		Q8N720	A0A1X7SBR3 P14136
PDB IDs		8PK6	6A9P
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition TRAF2-GSTP1 Complex Keratinization Intermediate Filament	Cytoskeleton Organization Intermediate Filament Organization Cytoskeleton Supramolecular Fiber Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Binding Protein Serine/threonine/tyrosine Kinase Activity Intracellular Signal Transduction Structural Constituent Of Skin Epidermis Cytoplasm Protein Kinase Activity Intermediate Filament Protein Serine Kinase Activity Regulation Of Cellular Component Organization Microtubule Cytoskeleton Organization Organelle Organization Response To Peptide Hormone Positive Regulation Of Signaling Regulation Of Generation Of Precursor Metabolites And Energy Protein Serine/threonine Kinase Activity Protein-containing Complex Keratin Filament Regulation Of Synaptic Plasticity Protein Phosphorylation Nucleus Kinase Activity Regulation Of Neuronal Synaptic Plasticity Structural Constituent Of Cytoskeleton Response To Hormone Regulation Of Protein Metabolic Process Positive Regulation Of Cell Communication Cytosol Regulation Of Sister Chromatid Segregation Regulation Of Cell Cycle Regulation Of Apoptotic Process Synaptic Membrane Mitotic Nuclear Membrane Disassembly Developmental Process Negative Regulation Of TORC1 Signaling Intracellular Signaling Cassette Regulation Of Proteolysis Phosphorylation Regulation Of Circadian Rhythm Regulation Of Signaling Positive Regulation Of Gene Expression Regulation Of Cell Communication Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Structural Molecule Activity
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