ZNF655 and DBF4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF655	DBF4B
Description		zinc finger protein 655	DBF4B-CDC7 kinase regulatory subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm Dbf4-dependent Protein Kinase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Serum metabolite levels ( 23093944)	Appendicular lean mass ( 33097823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		156 interacting genes: ACSL6 ANKRD11 AP1M1 ASB6 ASMTL ATOSB ATPAF2 BARD1 BORCS6 BYSL C8orf34 C8orf74 CAPN7 CARD9 CBY2 CCDC116 CCDC179 CCDC57 CCDC74A CCHCR1 CCNH CDC37 CDK4 CDR2L CEP57L1 CPNE7 CRACR2A CWF19L2 DBF4B DEUP1 DPF2 DUSP4 EGLN3 EIF4EBP1 EMILIN1 EVL EXOSC5 FADS2 FAM81A FAM81B FAM90A1 FARS2 FBXL9P FHL2 FKBP6 GEM GFAP GSTP1 GUCD1 HAPLN2 HEXIM2 HOMER3 HOOK1 HOXB5 HPCAL1 HSD3B7 HTT HUNK IDI1 IMP3 INTS10 INTS13 IP6K3 ITGB5 JRK KIFC3 KRT40 KRT76 KRT85 KRT86 KRTAP4-12 KRTAP5-9 KRTAP9-8 LCE3C LCE4A LCE5A LGALS14 LMO2 LNX1 MACO1 MAD2L2 MAGEA11 MAGEA2B MBD3 MED21 MEMO1 METTL21A MIS18A MITD1 MPP3 MRFAP1 MRPL28 MTMR9 MTUS2 MXI1 NAA10 NDC80 NECAB2 NGB NOTUM NUDT21 NUDT22 NXT2 OIP5 OSTF1 OTUD4 P2RX7 PBX3 PCSK5 PFKFB1 POLR1C PRR35 RIN3 RINT1 RRM1 RUNX1T1 SH2D4A SIGLEC6 SLC12A4 SMARCD1 SMG9 SPANXN2 SPRED1 SPRY3 SRGAP2B SZT2 TCEANC TEKT4 TEX28 THAP6 TIMM10 TLK1 TNS2 TRAF2 TRAF5 TRAPPC2 TRAPPC2B TRIM37 TRIM41 TRIM72 TRIP13 TSPYL4 TXNDC9 USHBP1 VAV1 VPS26C VPS9D1 XPA YPEL5 ZBTB16 ZC2HC1C ZNF330 ZNF552 ZNF648 ZNF792 ZNF837	17 interacting genes: CDC7 CYSRT1 GEM HEXIM2 HOXA1 KDM1A KRTAP4-12 LMO2 LRRK2 MDFI PCSK5 ROPN1 SGF29 SRPK2 SUV39H1 TRIM27 ZNF655
Entrez ID		79027	80174
HPRD ID		11673	16840
Ensembl ID		ENSG00000197343	ENSG00000161692
Uniprot IDs		Q8N720	Q8NFT6
PDB IDs		8PK6
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition TRAF2-GSTP1 Complex Keratinization Intermediate Filament	Identical Protein Binding Mitotic Spindle Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Epigenetic Regulation Of Gene Expression Regulation Of Cell Cycle Magnesium Ion Binding Nucleus Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Semicircular Canal Formation Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Abducens Nerve Formation Optokinetic Behavior Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Chromatin Organization Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Determination Of Adult Lifespan Regulation Of DNA Repair Regulation Of Neuroblast Proliferation Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Cellular Response To Curcumin Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly
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