SMU1 and MRFAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMU1	MRFAP1
Description		SMU1 DNA replication regulator and spliceosomal factor	Morf4 family associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		12 interacting genes: CD2BP2 CEBPA CERT1 H2BC21 LSM4 LSM8 MRFAP1 MSS51 RASSF10 TLX3 UBC YBX1	40 interacting genes: ABI1 ABI2 ABI3 BRK1 C3orf62 C8orf33 CAVIN3 CCDC146 DCDC2 DNAJB5 DPY30 FCHSD2 GOLGA8F GOLGA8G HTT KIFC3 MAP1LC3B MORF4L1 MORF4L2 MTIF3 PAM16 PCBD2 PCNT PRAP1 PRKAA2 SDCBP SH2D4A SMU1 SUV39H2 TEX11 TK1 TPM2 TRIM47 TXN TXN2 UBTD1 UQCC2 WASHC1 ZDHHC17 ZNF655
Entrez ID		55234	93621
HPRD ID		11588	17589
Ensembl ID		ENSG00000122692	ENSG00000179010
Uniprot IDs		A0MNN4 Q2TAY7	B3KQA0 Q9Y605
PDB IDs		5O9Z 6AHD 6Q8F 6Q8I 6Q8J 8H6K 8H6L 8QO9 8QZS
Enriched GO Terms of Interacting Partners?		U4/U6 X U5 Tri-snRNP Complex Nucleoplasm Lsm2-8 Complex U6 SnRNP U6 SnRNA Binding RNA Splicing MRNA Processing Spliceosomal SnRNP Assembly RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Metabolic Process Intermembrane Sphingolipid Transfer U2-type Precatalytic Spliceosome Response To Vitamin B2 C/EBP Complex Ceramide Transfer Activity CHOP-C/EBP Complex RNA Metabolic Process P-body RNA Processing Ribonucleoprotein Complex MiRNA Transport ER To Golgi Ceramide Transport	SCAR Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection Regulation Of Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Organelle Organization Regulation Of Lamellipodium Organization Regulation Of Organelle Organization Regulation Of Organelle Assembly Cytoskeleton Actin Filament Organization Neuron Migration Cell Projection Morphogenesis Centriole Filopodium Tip Signaling Adaptor Activity Autophagosome Lamellipodium
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