DCDC2 and PTPRCAP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DCDC2	PTPRCAP
Description		doublecortin domain containing 2	protein tyrosine phosphatase receptor type C associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cilium Axoneme Cell Projection Kinocilium	Plasma Membrane Membrane
	Molecular Function	Protein Binding Kinesin Binding	Protein Binding
	Biological Process	Neuron Migration Cellular Defense Response Nervous System Development Sensory Perception Of Sound Cell Projection Organization Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Smoothened Signaling Pathway Dendrite Morphogenesis Cilium Assembly Regulation Of Cilium Assembly	Defense Response
Pathways
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Estimated glomerular filtration rate ( 31015462 31152163) General cognitive ability ( 29844566) Information processing speed ( 21130836) Uric acid levels ( 21294900)	Refractive error ( 32231278) Ventral diencephalon volume ( 31530798)
Interacting Genes		19 interacting genes: APP B3GNT5 CENPO CKS1B COMMD9 DYNC2LI1 FAM118A KRTAP5-9 KRTAP9-3 LMO3 MICALL2 MRFAP1 NIF3L1 NMU POP5 PTPRCAP SLC38A2 TOLLIP ZNF432	3 interacting genes: DCDC2 EEF1A1 PTPRC
Entrez ID		51473	5790
HPRD ID		09308	09032
Ensembl ID		ENSG00000146038	ENSG00000213402
Uniprot IDs		Q9UHG0	Q14761
PDB IDs		2DNF
Enriched GO Terms of Interacting Partners?			Kinase Activator Activity Host-mediated Perturbation Of Viral Genome Replication Eukaryotic Translation Elongation Factor 1 Complex Cytoplasmic Side Of Lysosomal Membrane Host-mediated Activation Of Viral Genome Replication Regulation Of Chaperone-mediated Autophagy Protein Kinase Binding Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Gamma-delta T Cell Differentiation Positive Thymic T Cell Selection Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Microglial Cell Activation Negative Thymic T Cell Selection Positive Regulation Of Hematopoietic Stem Cell Migration Positive Regulation Of Isotype Switching To IgG Isotypes Protein Tyrosine Kinase Inhibitor Activity DN2 Thymocyte Differentiation Positive Regulation Of Gamma-delta T Cell Activation Membrane Raft Distribution Gamma-delta T Cell Differentiation Membrane Raft Localization Plasma Membrane Raft Distribution Membrane Microdomain Bleb Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Bone Marrow Development Negative T Cell Selection Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Gamma-delta T Cell Differentiation Kinocilium Alpha-beta T Cell Proliferation Positive T Cell Selection Regulation Of Isotype Switching To IgG Isotypes Negative Regulation Of Neuroinflammatory Response Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Negative Regulation Of Macrophage Activation Response To Aldosterone Regulation Of Microglial Cell Activation Transmembrane Receptor Protein Tyrosine Phosphatase Activity Translation Elongation Factor Activity Heparan Sulfate Proteoglycan Binding Ankyrin Binding Natural Killer Cell Differentiation Gamma-delta T Cell Activation Thymic T Cell Selection Positive Regulation Of Humoral Immune Response Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Alpha-beta T Cell Proliferation
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