DCDC2 and SLC38A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DCDC2	SLC38A2
Description		doublecortin domain containing 2	solute carrier family 38 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cilium Axoneme Cell Projection Kinocilium	Cytoplasm Plasma Membrane Brush Border Membrane Axon Dendrite Sarcolemma Neuronal Cell Body
	Molecular Function	Protein Binding Kinesin Binding	Amino Acid:sodium Symporter Activity Neutral L-amino Acid:sodium Symporter Activity Proline:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Acidic Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Symporter Activity Alanine:sodium Symporter Activity
	Biological Process	Neuron Migration Cellular Defense Response Nervous System Development Sensory Perception Of Sound Cell Projection Organization Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Smoothened Signaling Pathway Dendrite Morphogenesis Cilium Assembly Regulation Of Cilium Assembly	Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Neurotransmitter Transport Amino Acid Transport Glutamine Transport Female Pregnancy Positive Regulation Of Gene Expression Response To Muscle Activity Acidic Amino Acid Transport Neutral Amino Acid Transport Proline Transport L-serine Transport Cerebral Cortex Development Glycine Betaine Transport Alanine Transport Positive Regulation Of RNA Splicing Cellular Response To Amino Acid Starvation Sodium Ion Transmembrane Transport Amino Acid Import Cellular Response To Mechanical Stimulus Regulation Of Cellular Response To Stress Transport Across Blood-brain Barrier Regulation Of Glutamate Secretion, Neurotransmission L-glutamine Import Across Plasma Membrane L-serine Import Across Plasma Membrane Cellular Response To Arsenite(3-) L-proline Import Across Plasma Membrane
Pathways			Glutamate Neurotransmitter Release Cycle Amino acid transport across the plasma membrane
Drugs			Asparagine
Diseases
GWAS		Airflow obstruction ( 22837378) Estimated glomerular filtration rate ( 31015462 31152163) General cognitive ability ( 29844566) Information processing speed ( 21130836) Uric acid levels ( 21294900)	Appendicular lean mass ( 33097823) Blond vs. brown/black hair color ( 30531825) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Uterine fibroids ( 31649266)
Interacting Genes		19 interacting genes: APP B3GNT5 CENPO CKS1B COMMD9 DYNC2LI1 FAM118A KRTAP5-9 KRTAP9-3 LMO3 MICALL2 MRFAP1 NIF3L1 NMU POP5 PTPRCAP SLC38A2 TOLLIP ZNF432	4 interacting genes: APP DCDC2 STX11 TMEM237
Entrez ID		51473	54407
HPRD ID		09308	05535
Ensembl ID		ENSG00000146038	ENSG00000134294
Uniprot IDs		Q9UHG0	Q8NHT5 Q96QD8
PDB IDs		2DNF
Enriched GO Terms of Interacting Partners?			Regulation Of Wnt Signaling Pathway Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Plasma Membrane Bounded Cell Projection Organization Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Cell Projection Organization Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Neuron Projection Morphogenesis Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Cell Projection Cilium Assembly Cell Projection Morphogenesis Axon Choice Point Recognition Cone Photoreceptor Outer Segment Cilium Organization Heparan Sulfate Binding Signaling Receptor Activator Activity Kinocilium Peptidase Activator Activity Cellular Response To Manganese Ion Rod Photoreceptor Outer Segment Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Antifungal Humoral Response Nuclear Envelope Lumen
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