DNAJB5 and NOCT

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		DNAJB5	NOCT
Description		DnaJ heat shock protein family (Hsp40) member B5	nocturnin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	P-body Nucleus Nucleoplasm Cytoplasm Mitochondrion Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Unfolded Protein Binding Protein-folding Chaperone Binding	3'-5'-RNA Exonuclease Activity RNA Binding MRNA Binding Catalytic Activity Poly(A)-specific Ribonuclease Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Ester Bonds NADP Phosphatase Activity Metal Ion Binding NADPH Phosphatase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Folding Response To Unfolded Protein	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Nucleobase-containing Compound Metabolic Process Transcription By RNA Polymerase II NADP+ Metabolic Process Circadian Rhythm Negative Regulation Of Gene Expression Response To Lipopolysaccharide Circadian Regulation Of Gene Expression P-body Assembly Regulation Of Circadian Rhythm Positive Regulation Of Fat Cell Differentiation Negative Regulation Of Osteoblast Differentiation Regulation Of Embryonic Development MRNA Stabilization Rhythmic Process
Pathways			BMAL1:CLOCK,NPAS2 activates circadian expression
Drugs
Diseases
GWAS		Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		11 interacting genes: ANK2 CACNA1A MRFAP1 MYBPC1 NOCT OBSCN SMAD2 SMAD3 TAF1 TBPL2 TTN	1 interacting genes: DNAJB5
Entrez ID		25822	25819
HPRD ID		07106	16337
Ensembl ID		ENSG00000137094	ENSG00000151014
Uniprot IDs		A0A7I2RN43 O75953	Q9UK39
PDB IDs			6BT1 6BT2 6MAL 6NF0
Enriched GO Terms of Interacting Partners?		M Band Protein Localization To M-band Paraxial Mesoderm Morphogenesis Sarcomere Organization Structural Constituent Of Muscle Mesoderm Morphogenesis Pericardium Development SMAD Protein Complex Trophoblast Cell Migration Heteromeric SMAD Protein Complex Embryonic Foregut Morphogenesis Nodal Signaling Pathway Co-SMAD Binding Primary MiRNA Processing Titin Binding Transforming Growth Factor Beta Receptor Binding I-SMAD Binding Actomyosin Structure Organization Z Disc SMAD Protein Signal Transduction DNA-templated Transcription R-SMAD Binding Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Endoderm Development MiRNA Processing RNA Polymerase II-specific DNA-binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Ureteric Bud Development Negative Regulation Of Ossification Protein Stabilization Transcription Regulator Complex Gastrulation Mesonephric Epithelium Development Mesonephric Tubule Development Mesoderm Formation Nuclear Receptor Binding Nuclear Inner Membrane Myofibril Phosphatase Binding Protein Localization To T-tubule Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Androgen Receptor Signaling Pathway NADP Phosphatase Activity NADPH Phosphatase Activity Formation Of Primary Germ Layer Embryonic Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Osteoblast Differentiation
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