DNAJB5 and MYBPC1

Number of citations: 48 (PubMedID 23414517)
Data Source: BioGRID (two hybrid)

		DNAJB5	MYBPC1
Name		DnaJ heat shock protein family (Hsp40) member B5	myosin binding protein C1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Cytosol Myofibril M Band Myosin Filament
	Molecular Function	Protein Binding Unfolded Protein Binding Protein-folding Chaperone Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Myosin Binding Titin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Folding Response To Unfolded Protein	Cell Adhesion Sarcomere Organization
Pathways		None	Striated Muscle Contraction
GWAS		Response to quetiapine in schizophrenia ( 29503163 )	Lung function (FEV1) ( 24023788 ) Memory decline ( 31985465 )
Novel Interactors		1 novel interactors: SIGMAR1	None recorded
Interacting Genes		11 interacting genes: ANK2 CACNA1A MRFAP1 MYBPC1 NOCT OBSCN SMAD2 SMAD3 TAF1 TBPL2 TTN	27 interacting genes: ACO1 AMOT ANKRD1 ASH2L C1QTNF9 CALM1 CAPN3 CLIP4 DNAJB5 DNAJB6 DYSF FHL1 FHL2 FHL3 GABARAP GABARAPL1 GABARAPL2 KLHL41 MAP1LC3A MEOX2 MYBPC2 NCF1 RAF1 SGCG TRIM55 TRIM63 TTN
Entrez ID		25822	4604
HPRD ID		07106	01185
Ensembl ID		ENSG00000137094	ENSG00000196091
Uniprot IDs		A0A7I2RN43 O75953	A8KAB1 B3KPP3 Q00872
PDB IDs		Not available	1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM
GO Terms Enriched among Interactors		M Band Protein Localization To M-band Paraxial Mesoderm Morphogenesis Sarcomere Organization Structural Constituent Of Muscle Mesoderm Morphogenesis Pericardium Development SMAD Protein Complex Trophoblast Cell Migration Heteromeric SMAD Protein Complex Embryonic Foregut Morphogenesis Nodal Signaling Pathway Co-SMAD Binding Primary MiRNA Processing Titin Binding Transforming Growth Factor Beta Receptor Binding I-SMAD Binding Actomyosin Structure Organization Z Disc SMAD Protein Signal Transduction DNA-templated Transcription R-SMAD Binding Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Endoderm Development MiRNA Processing RNA Polymerase II-specific DNA-binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Ureteric Bud Development Negative Regulation Of Ossification Protein Stabilization Transcription Regulator Complex Gastrulation Mesonephric Epithelium Development Mesonephric Tubule Development Mesoderm Formation Nuclear Receptor Binding Nuclear Inner Membrane Myofibril Phosphatase Binding Protein Localization To T-tubule Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Androgen Receptor Signaling Pathway NADP Phosphatase Activity NADPH Phosphatase Activity Formation Of Primary Germ Layer Embryonic Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Osteoblast Differentiation	Cellular Response To Nitrogen Starvation Titin Binding Phosphatidylethanolamine Binding Actin Cytoskeleton Organization Z Disc M Band Cytoskeleton Organization Actin Filament-based Process Sarcomere Organization Actomyosin Structure Organization Autophagosome Maturation Phospholipid Binding Autophagosome Membrane Mitophagy GABA Receptor Binding Autophagy Of Mitochondrion Organelle Organization Autophagosome Response To Muscle Stretch Myofibril Assembly Autophagosome Assembly Autophagosome Organization Adenylate Cyclase Activator Activity Beta-tubulin Binding Structural Constituent Of Muscle Muscle Organ Development Response To Iron(II) Ion Muscle Structure Development Protein-containing Complex Disassembly Organelle Assembly Cytoplasm Macroautophagy Response To Metal Ion Vacuole Organization Microtubule Cellular Response To Starvation Pseudopodium Response To Starvation Cellular Response To Nutrient Levels Cytosol I Band Supramolecular Fiber Organization Response To Iron Ion Autophagy Response To Calcium Ion Ubiquitin Protein Ligase Binding Anatomical Structure Formation Involved In Morphogenesis Protein Binding Calcium-dependent Self Proteolysis Monocyte Activation Involved In Immune Response