MORF4L1 and TNIP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MORF4L1	TNIP1
Gene Name		mortality factor 4 like 1	TNFAIP3 interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Sin3 Complex NuA4 Histone Acetyltransferase Complex	Intracellular Nucleus Cytoplasm
	Molecular Function	Chromatin Binding Protein Binding Protein N-terminus Binding	Ubiquitin-specific Protease Activity Protein Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation	MyD88-dependent Toll-like Receptor Signaling Pathway Translation Defense Response Inflammatory Response Leukocyte Cell-cell Adhesion Glycoprotein Biosynthetic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Inflammatory Response Negative Regulation Of ERK1 And ERK2 Cascade Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Coronary heart disease ( 21378988)	Inflammatory bowel disease ( 23128233) Myasthenia gravis ( 23055271) Psoriasis ( 19169254) Systemic lupus erythematosus ( 23273568 19838193) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 21750679)
Protein-Protein Interactions		35 interactors: APP ARRDC3 BEND7 CALM1 CAMK2B CEP57L1 FAM9B FXR2 GMCL1 GOLGA2 HINFP HIST3H3 HMBOX1 IKZF1 L3MBTL3 LZTS2 MEOX1 MRFAP1 MRFAP1L1 MRGBP MSL1 NAB2 NAV2 PBXIP1 PHF12 RACGAP1 RB1 REL TFCP2 THAP1 TNIP1 TNNT1 TRIM41 ZBTB10 ZBTB9	61 interactors: ADH6 AP1M1 BYSL CCDC112 CCNG1 CDIP1 CDKN1A CFAP53 EFEMP1 EHHADH FAM161A FAM168A FUS GABARAPL1 GABARAPL2 GIT2 GTF2B GTF2H1 HDDC3 IKBKG KIFC3 MAGEB18 MAGEH1 MAP1LC3A MAP1LC3B MAPK1 MAPK10 MOB1B MOB3C MORF4L1 MORF4L2 NDC80 NFKB1 NIFK NME7 OPTN PIN1 PNKP RABAC1 RALBP1 RARA RARG RBFOX1 RNF11 RPL5 S100B SELPLG SNIP1 SUMO2 SYT6 TAX1BP1 TCEA2 TCEANC2 TNFAIP3 TNIP3 TTF2 TXLNA UBC VPS33B ZBTB25 ZNHIT1
Entrez ID		10933	10318
HPRD ID		09532	09216
Ensembl ID		ENSG00000185787	ENSG00000145901
Uniprot IDs		B3KTM8 Q9UBU8	A4F1W8 A4F1W9 A4F1X2 A8K4N4 B7Z8K2 E7EPY1 E7ET96 Q05KP3 Q05KP4 Q15025
PDB IDs		2AQL 2EFI 2F5J 2F5K 2LKM
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Gene Expression RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Spindle Midzone Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Transcription, DNA-templated Cell Cycle Immune System Process Multicellular Organismal Development Regulation Of Cell Division Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cell Division Neuron Maturation Cell Maturation Chromatin Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Neutrophil Differentiation Cytokinesis, Initiation Of Separation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade	Cellular Response To Stress MyD88-independent Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Toll-like Receptor 4 Signaling Pathway Activation Of Innate Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Stress Nucleophagy Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Macroautophagy Positive Regulation Of Innate Immune Response Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Mitochondrion Degradation MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Organelle Disassembly Autophagic Vacuole Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Cytokine Production Cellular Response To Nitrogen Starvation Cellular Response To Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Extracellular Stimulus I-kappaB Kinase/NF-kappaB Signaling Immune Response-regulating Signaling Pathway Membrane Fusion Innate Immune Response Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Metabolic Process Cellular Response To Starvation Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Response To Lipopolysaccharide Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Autophagy Response To Stimulus Fc Receptor Signaling Pathway Defense Response Transcription Initiation From RNA Polymerase II Promoter Response To External Stimulus
Tagcloud ?		aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly	1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing
Tagcloud (Difference) ?		aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly	1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 traits unreported utilizing
Tagcloud (Intersection) ?