MORF4L1 and BTG3

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		MORF4L1	BTG3
Description		mortality factor 4 like 1	BTG anti-proliferation factor 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex Sin3-type Complex	Nucleus Cytoplasm
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Chromatin Organization Regulation Of DNA-templated Transcription DNA Damage Response Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Fibroblast Proliferation Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Mitotic Cell Cycle
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254 33020668) Coronary heart disease ( 21378988) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730 31577861) Lung cancer in ever smokers ( 28604730) Myocardial infarction ( 33532862) Pulse pressure ( 27841878 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730)	Corpus callosum central volume ( 31530798) Feeling hurt ( 29500382)
Interacting Genes		83 interacting genes: APP ARID3A ARRDC3 BEND7 BEX5 BTG3 CALM1 CAMK2B CEBPA CEP57L1 CWC27 DMAP1 DRAP1 DSCR9 DYSF EP300 FAM13C FAM9B FBXO16 FHL3 FXR2 GMCL1 GOLGA2 GOLGA6A GSC2 H3-4 H3C1 HINFP HMBOX1 IKZF1 KPNA2 L3MBTL3 LHX2 LMNA LZTS2 MEOX1 MEOX2 MRFAP1 MRFAP1L1 MRGBP MRPL12 MSL1 NAB2 NAV2 NECAB1 NKD1 NMI PBXIP1 PCM1 PHF12 PIBF1 PICK1 PLEKHA3 PSMC1 RACGAP1 RB1 RCBTB2 REL SH3GLB2 SYN3 TEPSIN TEX11 TFCP2 THAP1 TLE5 TNIP1 TNNT1 TNNT2 TRIM41 TTC3 TULP3 UBP1 USO1 VPS26A ZBTB10 ZBTB26 ZBTB43 ZBTB8B ZBTB9 ZC3H7A ZNF276 ZNF438 ZNF449	76 interacting genes: ADNP2 AFF4 AGAP2 AHCYL1 AIP ATXN1 BANP CACNA1A CCDC13 CCT7 CLTC CLU CNOT7 CNOT8 CNTN4 COPS5 CREBZF CRYL1 DCLK2 DDX18 DIS3L DMAP1 DNAJC14 DNAJC7 DYNC1H1 EIF3C EIF3F EPRS1 GLUL HECTD2 HECTD4 HIVEP2 HSP90AA1 HSP90AB1 KCNQ2 KDM3A KIF3A MAPK8IP3 MORF4L1 MRPL38 MTM1 MYCBP2 NISCH NRBP1 OGT OSBPL8 OTOF PAK1 PAX6 PLA2G3 PLEKHB1 PPP2R5E PPP3CA PRKAR1A QARS1 RANBP9 RBL2 RNF10 RSPH1 SEC23IP SETDB1 SMG5 SPARCL1 SRPK2 SYNE1 TAF1 TAF6 TRIM32 TSC2 TSPAN7 USP8 WAPL WDFY3 XPC ZNF532 ZNF592
Entrez ID		10933	10950
HPRD ID		09532	10415
Ensembl ID		ENSG00000185787	ENSG00000154640
Uniprot IDs		Q9UBU8	Q14201 Q6IAU3
PDB IDs		2AQL 2EFI 2F5J 2F5K 2LKM 2N1D 6AGO 6INE 7S4A 8BPA 8C60
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleoplasm Nucleus Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Spermatogonial Cell Division Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process Rb-E2F Complex Somite Specification Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Transcription Coregulator Activity Negative Regulation Of Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Transcription Corepressor Activity Troponin Complex Chromatin Organization Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Importin-alpha Family Protein Binding Regulation Of Protein Localization To Nucleus Positive Regulation Of Metabolic Process Regulation Of Skeletal Muscle Adaptation DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Cytosol Cytoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Establishment Of Localization In Cell Regulation Of Macromolecule Biosynthetic Process Eukaryotic Translation Initiation Factor 3 Complex Organelle Organization Nucleus Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Metabolic Process RNA Binding Cytoskeleton Organization Chaperone-mediated Protein Complex Assembly Protein Localization To Organelle Translation Initiation Factor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Unfolded Protein Binding Regulation Of Gene Expression Translation Intracellular Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Intracellular Protein Localization Disordered Domain Specific Binding Regulation Of Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Telomerase Holoenzyme Complex Assembly Negative Regulation Of Catabolic Process CCR4-NOT Core Complex Chromatin Organization 3'-5'-RNA Exonuclease Activity Positive Regulation Of Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Gene Expression Nucleoplasm Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding ATP-dependent Protein Folding Chaperone
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