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GTF3C4 and POLR3C
Number of citations of the paper that reports this interaction (PMID
10523658
)
26
Data Source:
HPRD
(in vivo, in vitro)
GTF3C4
POLR3C
Gene Name
general transcription factor IIIC, polypeptide 4, 90kDa
polymerase (RNA) III (DNA directed) polypeptide C (62kD)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Transcription Factor TFIIIC Complex
Nucleoplasm
Nucleus
Nucleoplasm
DNA-directed RNA Polymerase III Complex
Cytosol
Molecular Function
DNA Binding
Histone Acetyltransferase Activity
Protein Binding
Enzyme Activator Activity
RNA Polymerase III Activity
DNA Binding
DNA-directed RNA Polymerase Activity
Biological Process
Transcription, DNA-templated
Transcription From RNA Polymerase III Promoter
Transcription Initiation From RNA Polymerase III Promoter
Gene Expression
Histone Acetylation
5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
TRNA Transcription From RNA Polymerase III Promoter
Positive Regulation Of Catalytic Activity
Regulation Of Transcription From RNA Polymerase III Promoter
Transcription From RNA Polymerase III Promoter
Transcription Elongation From RNA Polymerase III Promoter
Termination Of RNA Polymerase III Transcription
Gene Expression
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-beta Production
Innate Immune Response
Positive Regulation Of Innate Immune Response
Defense Response To Virus
Pathways
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Termination
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase III Abortive And Retractive Initiation
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Initiation From Type 2 Promoter
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
11 interactors:
BRCA1
BRF1
GTF3C1
GTF3C2
GTF3C5
GTF3C6
HIST2H3A
HIST3H3
POLR3C
POLR3F
TBP
8 interactors:
APP
CEP63
GTF3C4
PNMA5
ROCK1
ROPN1
TNR
TRIM27
Entrez ID
9329
10623
HPRD ID
11998
17880
Ensembl ID
ENSG00000186141
Uniprot IDs
B3KNH2
Q9UKN8
Q9BUI4
PDB IDs
2XUB
2XV4
Enriched GO Terms of Interacting Partners
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Transcription From RNA Polymerase III Promoter
TRNA Transcription
5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
TRNA Transcription From RNA Polymerase III Promoter
RRNA Transcription
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase III Promoter
Transcription, DNA-templated
Gene Expression
RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
DNA-templated Transcription, Termination
DNA-templated Transcription, Elongation
RNA Metabolic Process
Biosynthetic Process
Chromatin Silencing At RDNA
Termination Of RNA Polymerase III Transcription
Transcription Elongation From RNA Polymerase III Promoter
Positive Regulation Of Interferon-beta Production
Cellular Metabolic Process
Regulation Of Gene Expression, Epigenetic
Chromatin Silencing
Regulation Of Interferon-beta Production
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Positive Regulation Of Cytokine Production
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Histone H3-K9 Acetylation
Gene Silencing
Regulation Of Type I Interferon Production
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Proepicardium Development
Regulation Of Cytokine Production
Cellular Response To Indole-3-methanol
Defense Response To Virus
Metabolic Process
Negative Regulation Of Centriole Replication
Dosage Compensation By Inactivation Of X Chromosome
Positive Regulation Of Innate Immune Response
Protein K6-linked Ubiquitination
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Axon Guidance
Neuromuscular Process Controlling Balance
Associative Learning
Negative Regulation Of Axon Extension Involved In Regeneration
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Negative Regulation Of Interleukin-2 Secretion
Synaptic Growth At Neuromuscular Junction
Neuromuscular Process
Neuron Projection Morphogenesis
Learning
Collateral Sprouting In Absence Of Injury
Cell Morphogenesis Involved In Differentiation
Synapse Organization
Cellular Component Assembly
Neuron Projection Development
Negative Regulation Of Neuron Differentiation
Collateral Sprouting
Axon Midline Choice Point Recognition
Membrane To Membrane Docking
Cell Projection Morphogenesis
Cell Part Morphogenesis
5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
TRNA Transcription From RNA Polymerase III Promoter
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Calcium Ion Import
Apical Constriction
Axon Choice Point Recognition
TRNA Transcription
Locomotory Behavior
Neuron Development
Negative Regulation Of Axon Regeneration
Positive Regulation Of Transmission Of Nerve Impulse
Interferon-gamma Secretion
Learning Or Memory
Neuron Remodeling
Cell Morphogenesis
Bleb Assembly
Regulation Of Developmental Growth
Negative Regulation Of Neurogenesis
Cognition
Cytoskeleton Organization
Neuron Differentiation
Cell Projection Organization
Regulation Of Transmission Of Nerve Impulse
Centriole Replication
Locomotory Exploration Behavior
Positive Regulation Of Cellular Component Biogenesis
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