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GTF3C4 and BRF1
Number of citations of the paper that reports this interaction (PMID
10523658
)
26
Data Source:
HPRD
(in vivo, in vitro)
GTF3C4
BRF1
Gene Name
general transcription factor IIIC, polypeptide 4, 90kDa
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Transcription Factor TFIIIC Complex
Nucleoplasm
Transcription Factor TFIIIB Complex
Nucleoplasm
Molecular Function
DNA Binding
Histone Acetyltransferase Activity
Protein Binding
Enzyme Activator Activity
Zinc Ion Binding
TBP-class Protein Binding
Biological Process
Transcription, DNA-templated
Transcription From RNA Polymerase III Promoter
Transcription Initiation From RNA Polymerase III Promoter
Gene Expression
Histone Acetylation
5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
TRNA Transcription From RNA Polymerase III Promoter
Positive Regulation Of Catalytic Activity
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase III Promoter
Transcription Initiation From RNA Polymerase III Promoter
RRNA Transcription
TRNA Transcription
Gene Expression
Regulation Of MRNA Stability
Pathways
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS
Mean platelet volume (
22139419
)
Protein-Protein Interactions
11 interactors:
BRCA1
BRF1
GTF3C1
GTF3C2
GTF3C5
GTF3C6
HIST2H3A
HIST3H3
POLR3C
POLR3F
TBP
13 interactors:
APP
CSNK2A1
DTNBP1
GTF3C3
GTF3C4
GTF3C5
PCBD2
POLR3F
RB1
RBL1
RBL2
TBP
TP53
Entrez ID
9329
2972
HPRD ID
11998
05361
Ensembl ID
ENSG00000185024
Uniprot IDs
B3KNH2
Q9UKN8
Q92994
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase III Promoter
TRNA Transcription
5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
TRNA Transcription From RNA Polymerase III Promoter
RRNA Transcription
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase III Promoter
Transcription, DNA-templated
Gene Expression
RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
DNA-templated Transcription, Termination
DNA-templated Transcription, Elongation
RNA Metabolic Process
Biosynthetic Process
Chromatin Silencing At RDNA
Termination Of RNA Polymerase III Transcription
Transcription Elongation From RNA Polymerase III Promoter
Positive Regulation Of Interferon-beta Production
Cellular Metabolic Process
Regulation Of Gene Expression, Epigenetic
Chromatin Silencing
Regulation Of Interferon-beta Production
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Positive Regulation Of Cytokine Production
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Histone H3-K9 Acetylation
Gene Silencing
Regulation Of Type I Interferon Production
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Proepicardium Development
Regulation Of Cytokine Production
Cellular Response To Indole-3-methanol
Defense Response To Virus
Metabolic Process
Negative Regulation Of Centriole Replication
Dosage Compensation By Inactivation Of X Chromosome
Positive Regulation Of Innate Immune Response
Protein K6-linked Ubiquitination
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Transcription From RNA Polymerase III Promoter
RRNA Transcription
5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
TRNA Transcription From RNA Polymerase III Promoter
TRNA Transcription
Transcription, DNA-templated
RNA Metabolic Process
RNA Biosynthetic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Biosynthetic Process
Macromolecule Biosynthetic Process
Neuron Apoptotic Process
Regulation Of Lipid Kinase Activity
Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Neuron Death
Positive Regulation Of Gene Expression
Regulation Of Cell Cycle Phase Transition
Glial Cell Apoptotic Process
Positive Regulation Of Metabolic Process
Regulation Of Gene Expression
Chromatin Organization
Mitotic Cell Cycle
Positive Regulation Of Transcription, DNA-templated
Regulation Of Mitotic Cell Cycle
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Mitotic Cell Cycle Checkpoint
Regulation Of RNA Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Cell Cycle Process
Regulation Of Metabolic Process
Neuron Maturation
Chromosome Organization
Regulation Of Chromosome Organization
Viral Process
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Cell Cycle Process
Regulation Of Nitrogen Compound Metabolic Process
DNA-templated Transcription, Initiation
Tagcloud
?
5s
alcohol
cjun
colony
consumption
decreases
deregulation
downregulate
enhances
eralpha
iii
indicates
inhibits
jun
occupancy
pol
promoters
reduces
repress
repressing
repression
rrna
tam
tamoxifen
transcription
translational
trnas
uncover
upregulate
Tagcloud (Difference)
?
5s
alcohol
cjun
colony
consumption
decreases
deregulation
downregulate
enhances
eralpha
iii
indicates
inhibits
jun
occupancy
pol
promoters
reduces
repress
repressing
repression
rrna
tam
tamoxifen
transcription
translational
trnas
uncover
upregulate
Tagcloud (Intersection)
?