RNF19A and NUDT21

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RNF19A	NUDT21
Gene Name		ring finger protein 19A, RBR E3 ubiquitin protein ligase	nudix (nucleoside diphosphate linked moiety X)-type motif 21
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Integral Component Of Membrane	Nucleus Nucleoplasm Centrosome MRNA Cleavage Factor Complex Paraspeckles
	Molecular Function	Transcription Factor Binding Zinc Ion Binding Ligase Activity	RNA Binding MRNA Binding Protein Binding Hydrolase Activity AU-rich Element Binding Protein Homodimerization Activity Histone Deacetylase Binding Poly(A) RNA Binding
	Biological Process	Microtubule Cytoskeleton Organization Protein Ubiquitination	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Processing RNA Splicing Gene Expression MRNA 3'-end Processing Protein Tetramerization
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs mRNA 3'-end processing
Drugs
Diseases
GWAS		Atrioventricular conduction ( 21041692)
Protein-Protein Interactions		16 interactors: C11orf58 CASR ILK MAP3K7 NUDT21 RPS6KA5 SNCAIP SOD1 SUFU TUBG1 TUBG2 UBE2E2 UBE2L3 UBE2L6 VCP ZAK	51 interactors: A2M ATXN1 CARM1 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G EXOSC6 F13A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIAA1377 KIFAP3 MASP1 MYL6 NEDD4 NGEF NIF3L1 POLR2C PSMF1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 SEMA5B SF3B1 SHC1 SHFM1 SLC44A1 SNCAIP SNRNP70 SRPK1 TCERG1 TLE1 TRA2A TRIM27 WWOX ZBTB48
Entrez ID		25897	11051
HPRD ID		06176	05400
Ensembl ID		ENSG00000034677	ENSG00000167005
Uniprot IDs		Q9NV58	O43809
PDB IDs			2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Modification Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Cellular Protein Metabolic Process ISG15-protein Conjugation Positive Regulation Of Protein Metabolic Process Positive Regulation Of MAP Kinase Activity MAPK Cascade Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity JNK Cascade Cellular Response To Stress Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Catalytic Activity Signal Transduction By Phosphorylation Regulation Of Protein Metabolic Process Regulation Of MAP Kinase Activity Positive Regulation Of Protein Phosphorylation Microtubule Nucleation Epithelial Tube Morphogenesis Protein K11-linked Ubiquitination Cellular Response To Organic Substance Activation Of MAPK Activity Response To Stress Microtubule Polymerization Tube Morphogenesis Positive Regulation Of MAPK Cascade Positive Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Vasodilation Positive Regulation Of Kinase Activity Cytoplasmic Microtubule Organization Morphogenesis Of An Epithelium Microtubule Polymerization Or Depolymerization Regulation Of Cytokine Production Protein Complex Assembly Cell Cycle Process Myelination In Peripheral Nervous System Regulation Of Catalytic Activity Protein Ubiquitination Cellular Protein Modification Process Regulation Of Protein Phosphorylation Schwann Cell Development Epithelium Development Toll-like Receptor 5 Signaling Pathway Protein Modification By Small Protein Conjugation Toll-like Receptor 10 Signaling Pathway Regulation Of MAPK Cascade Cell Cycle Phase Transition Response To Organic Substance	Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Process Cellular Metabolic Process Viral Process Protein K63-linked Ubiquitination RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Protein Polyubiquitination Negative Regulation Of Complement Activation MRNA 3'-end Processing Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Immune System Process Developmental Process RNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Regulation Of Dendrite Development Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression By Genetic Imprinting Blood Coagulation Macromolecule Biosynthetic Process Hemostasis Protein Oligomerization MRNA Polyadenylation Anatomical Structure Development
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