MYOZ1 and YPEL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYOZ1	YPEL3
Description		myozenin 1	yippee like 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Actin Cytoskeleton Z Disc Pseudopodium Cell Projection	Nucleus Nucleolus
	Molecular Function	Actin Binding Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Telethonin Binding Actinin Binding FATZ Binding Molecular Condensate Scaffold Activity	Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Myofibril Assembly Wound Healing Negative Regulation Of Skeletal Muscle Tissue Regeneration Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade	Positive Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 25056061 28991256 29483656)
Interacting Genes		42 interacting genes: ACTN1 ACTN2 ACTN3 ACTN4 AKAP8L APP BAG4 BRCA1 CEACAM6 CEP76 CRX EIF3F EXOSC8 FBXL21P FLNA FLNC GOLGA6A GRB2 GSK3B KRT34 KRT36 KRTAP12-2 LDB3 LHX4 LZTS2 MAGEA11 PFDN5 PLEKHG4 PNKP PNMA1 PRKAA2 TCAP TRAF1 TRIM23 TRIM55 TRIM63 USHBP1 VAC14 VBP1 WASHC3 WWOX YPEL3	122 interacting genes: ACTMAP AIRIM APP ARMC7 ATG9A ATXN1L BCAS2 C10orf55 CABP2 CDCA4 CDKN2D COL8A1 CRYBA1 CRYBA2 CYB5R2 CYSRT1 DMRT3 DOK6 DOK7 EID2B FAM168B FANCL FGF21 FHL2 FHL3 FHL5 FNDC3B FRS3 GCA GCM2 GEM GUCD1 HDAC7 HEXIM2 HGS HNRNPH1 HOXA1 HR HSD3B7 HSPB2 HSPB2-C11orf52 INTS11 KLHL38 KRTAP13-2 KRTAP15-1 KRTAP23-1 KRTAP3-1 KRTAP3-3 KRTAP6-2 LARP4 LIMS3 LIMS4 LMO2 LONRF1 MAD2L2 MDFI MKRN3 MORN3 MYOZ1 MYOZ3 NRF1 NUFIP2 ODAM OSTF1 OTX1 PIK3R3 PITX1 PLSCR4 POLD1 POLR1C POU2AF1 PPP2CA PRKAA2 PRKAB2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 QRICH1 RBPMS RFC5 SH2D4A SHC3 SMUG1 SPAG8 SPG21 SPRYD7 SRPK2 STK16 TASOR2 TBX6 TENT5A TENT5B TEPSIN TGM7 TLE5 TLX3 TOX2 TP53INP1 TRAPPC2L TRAPPC6A TRIM10 TRIM55 TRIM63 TRIM73 TRIP6 TSC1 TSSK3 UBASH3A UBTD2 VENTX VGLL3 VWC2L WWOX ZIC1 ZNF441 ZNF76 ZNF765 ZYX
Entrez ID		58529	83719
HPRD ID		05725	15683
Ensembl ID		ENSG00000177791	ENSG00000090238
Uniprot IDs		Q9NP98	P61236
PDB IDs		7A8T 7A8U 7ANK
Enriched GO Terms of Interacting Partners?		Z Disc Pseudopodium Muscle Cell Development Actin Cytoskeleton Organization Actin Filament-based Process Regulation Of Apoptotic Process Transmembrane Transporter Binding Regulation Of Programmed Cell Death Identical Protein Binding Cytoskeleton Organization Sarcomere Organization Titin Binding Regulation Of Supramolecular Fiber Organization Titin Z Domain Binding Actin Filament Binding Regulation Of Glycolytic Process Cortical Actin Cytoskeleton Sarcomere Regulation Of Amyloid Fibril Formation Regulation Of Generation Of Precursor Metabolites And Energy Platelet Alpha Granule Lumen Regulation Of Carbohydrate Catabolic Process Cytoskeletal Protein Binding Integrin Binding Actin Binding Regulation Of ATP Metabolic Process Regulation Of Cytoskeleton Organization Focal Adhesion Assembly Cytosol Cytoplasm Actin Filament Positive Regulation Of Supramolecular Fiber Organization FATZ Binding Skeletal Muscle Atrophy Regulation Of Purine Nucleotide Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Cell-substrate Junction Assembly Skeletal Muscle Adaptation Striated Muscle Atrophy Prefoldin Complex Cell-substrate Junction Organization Anatomical Structure Morphogenesis Structural Constituent Of Muscle Actomyosin Structure Organization Supramolecular Fiber Organization Organelle Organization Muscle Atrophy Positive Regulation Of Organelle Organization Cell Development	Protein Binding Nucleus
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