LY6E and FCGR2B

Number of citations of the paper that reports this interaction (PMID 11576217)
2

Data Source:
HPRD (in vivo)

		LY6E	FCGR2B
Gene Name		lymphocyte antigen 6 complex, locus E	Fc fragment of IgG, low affinity IIb, receptor (CD32)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Anchored Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function		Protein Binding IgG Binding
	Biological Process	In Utero Embryonic Development Cell Surface Receptor Signaling Pathway Adrenal Gland Development Organ Growth Norepinephrine Metabolic Process Epinephrine Secretion Ventricular Cardiac Muscle Tissue Morphogenesis	Immune Response Signal Transduction Viral Process Regulation Of Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Lipid metabolism phenotypes ( 22286219) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		2 interactors: CD247 FCGR2B	11 interactors: APCS BLK C14orf1 CRP INPP5D INPPL1 LY6E LYN MAPK1 MAPK3 PTPN6
Entrez ID		4061	2213
HPRD ID		03227	06849
Ensembl ID		ENSG00000160932	ENSG00000072694
Uniprot IDs		Q16553	P31994
PDB IDs			2FCB
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Immune Response Regulation Of Defense Response To Virus By Virus Immune Response Regulation Of Immune System Process T Cell Costimulation Regulation Of Defense Response To Virus Immune System Process T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation	JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Immune Response-activating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Response To Growth Hormone Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway JAK-STAT Cascade Immune Response Regulation Of Immune System Process Response To Peptide Hormone Immune System Process Immune Response-regulating Signaling Pathway Regulation Of Immune Response Response To Peptide Positive Regulation Of Immune System Process Wound Healing Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Response To Wounding Defense Response Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response Peptidyl-tyrosine Autophosphorylation Response To Organonitrogen Compound Blood Coagulation Hemostasis Regulation Of Golgi Inheritance Cellular Response To Organonitrogen Compound Platelet Activation Response To Hormone Negative Regulation Of Myeloid Leukocyte Differentiation Caveolin-mediated Endocytosis Regulation Of Cellular Localization Cellular Response To Heat Regulation Of Body Fluid Levels Negative Regulation Of Monocyte Differentiation Cellular Response To Hormone Stimulus Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Phagocytosis Regulation Of Golgi Organization Leukocyte Mediated Immunity Negative Regulation Of Leukocyte Proliferation Peptidyl-tyrosine Phosphorylation Endocytosis Response To Insulin Regulation Of MAP Kinase Activity
Tagcloud ?			arm arms benefit carriers concurrently deriving dfs equivocal fcgammar fcgr3a genotypes genotypic genotyping i232t igg1 killer log n9831 polymorphisms pooled portion proportional r131h rank sequentially superior trastuzumab v158f
Tagcloud (Difference) ?			arm arms benefit carriers concurrently deriving dfs equivocal fcgammar fcgr3a genotypes genotypic genotyping i232t igg1 killer log n9831 polymorphisms pooled portion proportional r131h rank sequentially superior trastuzumab v158f
Tagcloud (Intersection) ?