DYRK1B and RANBP9

Number of citations of the paper that reports this interaction (PMID 14500717)
21

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vivo, in vitro)

		DYRK1B	RANBP9
Gene Name		dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	RAN binding protein 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytosol Microtubule Associated Complex
	Molecular Function	Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Protein Phosphorylation Myoblast Fusion Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription, DNA-templated Adipose Tissue Development	Protein Complex Assembly Microtubule Nucleation Axon Guidance
Pathways			Axon guidance L1CAM interactions
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		11 interactors: DCAF7 HDAC5 LZTS2 MAP2K3 MAPK1 MAPK14 MBP PAK1 PCBD1 RANBP9 TROAP	51 interactors: ADAP1 ADAP2 APC AR AXL BACE1 BRCA1 CACNA1G CALB1 CBS CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 OPRM1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1
Entrez ID		9149	10048
HPRD ID		05188	04835
Ensembl ID		ENSG00000105204	ENSG00000010017
Uniprot IDs		B4DXU2 Q9Y463	Q96S59
PDB IDs
Enriched GO Terms of Interacting Partners?		Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of MAP Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway MAPK Cascade Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Toll-like Receptor 4 Signaling Pathway Regulation Of MAP Kinase Activity Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of MAPK Cascade Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Response To Peptide Positive Regulation Of Kinase Activity Positive Regulation Of Innate Immune Response Positive Regulation Of Transferase Activity Cellular Response To Insulin Stimulus Chemotaxis Regulation Of MAPK Cascade Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Immune Response Immune Response Regulation Of Innate Immune Response Immune System Process Positive Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Peptidyl-threonine Phosphorylation Nuclear Transport Multicellular Organismal Development Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Response To Insulin Regulation Of Myotube Differentiation	Multicellular Organismal Development Anatomical Structure Development Developmental Process System Development Organ Development Response To Organic Substance Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Organic Substance Signal Transduction Cellular Response To Organic Cyclic Compound Signaling DNA-templated Transcription, Initiation Cellular Response To Stimulus Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Response To Stimulus Response To Organic Cyclic Compound Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Tissue Development Response To Lipid Nervous System Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Steroid Hormone Mediated Signaling Pathway Response To Growth Factor Epithelium Development Wound Healing Negative Regulation Of Signal Transduction Regulation Of Cell Proliferation Response To Hormone Reproductive Process Regulation Of Intracellular Signal Transduction Apoptotic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Hormone-mediated Signaling Pathway Cell Activation Negative Regulation Of Signaling DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Tagcloud ?		2a balance bm88 brdu bromo cend1 coordination cytosolic deoxyuridine destabilization elucidate exit incorporation lineage modulator neuro neuroblastoma neuronal partner pivotal precursors ran ranbpm retention reverted scaffolding stabilizes transiently	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Difference) ?		2a balance bm88 brdu bromo cend1 coordination cytosolic deoxyuridine destabilization elucidate exit incorporation lineage modulator neuro neuroblastoma neuronal partner pivotal precursors ran ranbpm retention reverted scaffolding stabilizes transiently	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Intersection) ?