DYRK1B and DCAF7

Number of citations of the paper that reports this interaction (PMID 14593110)
19

Data Source:
HPRD (in vitro)

		DYRK1B	DCAF7
Gene Name		dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	DDB1 and CUL4 associated factor 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Nuclear Matrix Protein Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Protein Phosphorylation Myoblast Fusion Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription, DNA-templated Adipose Tissue Development	Multicellular Organismal Development Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: DCAF7 HDAC5 LZTS2 MAP2K3 MAPK1 MAPK14 MBP PAK1 PCBD1 RANBP9 TROAP	6 interactors: APP ATP13A2 BMPR1B DYRK1B MAP3K1 YWHAG
Entrez ID		9149	10238
HPRD ID		05188	09340
Ensembl ID		ENSG00000105204	ENSG00000136485
Uniprot IDs		B4DXU2 Q9Y463	P61962
PDB IDs
Enriched GO Terms of Interacting Partners?		Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of MAP Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway MAPK Cascade Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Toll-like Receptor 4 Signaling Pathway Regulation Of MAP Kinase Activity Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of MAPK Cascade Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Response To Peptide Positive Regulation Of Kinase Activity Positive Regulation Of Innate Immune Response Positive Regulation Of Transferase Activity Cellular Response To Insulin Stimulus Chemotaxis Regulation Of MAPK Cascade Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Immune Response Immune Response Regulation Of Innate Immune Response Immune System Process Positive Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Peptidyl-threonine Phosphorylation Nuclear Transport Multicellular Organismal Development Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Response To Insulin Regulation Of Myotube Differentiation	Protein Phosphorylation Cell Differentiation Synaptic Growth At Neuromuscular Junction Ovarian Cumulus Expansion Negative Regulation Of Chondrocyte Proliferation Phosphorylation Cell Morphogenesis Involved In Differentiation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Collateral Sprouting In Absence Of Injury System Development Positive Regulation Of Apoptotic Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Manganese Ion Apoptotic Process Anatomical Structure Morphogenesis Programmed Cell Death Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Oogenesis Stage Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Connective Tissue Development Cell Death Death Cell Morphogenesis Multicellular Organismal Development Axon Choice Point Recognition Antral Ovarian Follicle Growth Regulation Of Protein Phosphorylation Anatomical Structure Development Signal Transduction By Phosphorylation Developmental Growth Neuron Remodeling Regulation Of Signal Transduction Phosphate-containing Compound Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Organ Development Defense Response Developmental Process Camera-type Eye Development Regulation Of Signaling Axon Guidance Cellular Protein Modification Process Eye Development Positive Regulation Of Organelle Organization Regulation Of Phosphorus Metabolic Process Eyelid Development In Camera-type Eye Response To Manganese Ion Cellular Copper Ion Homeostasis
Tagcloud ?		2a balance bm88 brdu bromo cend1 coordination cytosolic deoxyuridine destabilization elucidate exit incorporation lineage modulator neuro neuroblastoma neuronal partner pivotal precursors ran ranbpm retention reverted scaffolding stabilizes transiently
Tagcloud (Difference) ?		2a balance bm88 brdu bromo cend1 coordination cytosolic deoxyuridine destabilization elucidate exit incorporation lineage modulator neuro neuroblastoma neuronal partner pivotal precursors ran ranbpm retention reverted scaffolding stabilizes transiently
Tagcloud (Intersection) ?