DYRK1B and DCAF7

Number of citations of the paper that reports this interaction (PubMedID 14593110)
0

Data Source:
HPRD (in vitro)

		DYRK1B	DCAF7
Description		dual specificity tyrosine phosphorylation regulated kinase 1B	DDB1 and CUL4 associated factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Nucleotide Binding Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	DNA Repair Protein Phosphorylation DNA Damage Response Myoblast Fusion Positive Regulation Of DNA-templated Transcription Adipose Tissue Development	Protein Ubiquitination
Pathways			Association of TriC/CCT with target proteins during biosynthesis Neddylation
Drugs		Fostamatinib
Diseases
GWAS		Macular thickness ( 30535121)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		12 interacting genes: DCAF7 GSC2 HDAC5 ID2 MAP2K3 MAPK1 MAPK14 MBP PAK1 PCBD1 RANBP9 TROAP	7 interacting genes: APP ATP13A2 BMPR1B DYRK1B LIG1 PWP2 YWHAG
Entrez ID		9149	10238
HPRD ID		05188	09340
Ensembl ID		ENSG00000105204	ENSG00000136485
Uniprot IDs		A0A9H4CVU7 Q9Y463	P61962
PDB IDs		8C2Z
Enriched GO Terms of Interacting Partners?		MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Muscle Cell Differentiation Cellular Senescence NLRP1 Inflammasome Complex Assembly Negative Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Cellular Response To UV-B MAP Kinase Activity MAP Kinase Kinase Activity Response To Lipopolysaccharide Mammary Gland Epithelial Cell Proliferation Response To Molecule Of Bacterial Origin Regulation Of Blood Vessel Endothelial Cell Migration Protein Serine Kinase Activity Response To UV-B Stress-activated MAPK Cascade Protein-containing Complex Negative Regulation Of Hippo Signaling P38MAPK Cascade Protein Serine/threonine Kinase Activity Intracellular Signaling Cassette Cellular Response To Vascular Endothelial Growth Factor Stimulus Response To Insulin Nucleoplasm Cellular Response To Lipopolysaccharide Astrocyte Differentiation Canonical Inflammasome Complex Assembly Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Erythrocyte Differentiation Cellular Response To Molecule Of Bacterial Origin Regulation Of Endothelial Cell Migration Cytosol Protein Kinase Activity Lipopolysaccharide-mediated Signaling Pathway Regulation Of Cell Migration Negative Regulation Of Striated Muscle Cell Differentiation Pyroptotic Inflammatory Response Regulation Of Cell Motility Regulation Of Hippo Signaling Regulation Of Myotube Differentiation Positive Regulation Of Cell Migration Regulation Of Locomotion Positive Regulation Of Cell Motility Regulation Of Erythrocyte Differentiation Positive Regulation Of Locomotion Positive Regulation Of Metabolic Process Kinase Activity Positive Regulation Of Metalloendopeptidase Activity Heart Development	Cellular Response To Manganese Ion Response To Manganese Ion Cellular Response To Stress
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?